Acquired perforating dermatosis: A clinical and dermatoscopic correlation

Ramirez-Fort, Marigdalia K., Khan, Farhan, Rosendahl, Cliff O., Mercer, Stephen E., Shim-Chang, Helen and Levitt, Jacob O. (2013) Acquired perforating dermatosis: A clinical and dermatoscopic correlation. Dermatology Online Journal, 19 7: .

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Author Ramirez-Fort, Marigdalia K.
Khan, Farhan
Rosendahl, Cliff O.
Mercer, Stephen E.
Shim-Chang, Helen
Levitt, Jacob O.
Title Acquired perforating dermatosis: A clinical and dermatoscopic correlation
Journal name Dermatology Online Journal   Check publisher's open access policy
ISSN 1087-2108
Publication date 2013-07
Year available 2013
Sub-type Article (original research)
Open Access Status File (Publisher version)
Volume 19
Issue 7
Total pages 4
Formatted abstract
Acquired perforating dermatosis (APD) is a perforating disease characterized by transepidermal elimination of dermal material. This disease usually develops in adulthood. APD has been most commonly associated with dialysis dependent chronic renal failure or diabetes mellitus. We present a case of a 65-year-old female with a 6-month history of multiple hyperpigmented, follicular keratotic papulonodular lesions located on the lower extremities. Histologic examination demonstrated perforating folliculitis, consistent with the diagnosis of perforating dermatosis. Dermatoscopic imaging with polarized light supported the histological findings. Clinical and histological presentation of APD may vary vastly from patient to patient. Lesions within the same patient may differ by the dermal component that is being transepidermally extruded. For these reasons, authors have suggested multiple biopsies. We have found the utility of dermatoscopy in visualizing gross histologic features. Dermatoscopy allows for improved in vivo visualization and may aide in distinguishing APD from simple prurigo nodularis.
Keyword Dermatosis
Q-Index Code CX
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Non HERDC
School of Medicine Publications
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Created: Thu, 28 Nov 2013, 17:29:59 EST by System User on behalf of School of Medicine