Electrochemically-gated delivery of analyte bands in microfluidic devices using bipolar electrodes

Scida, Karen, Sheridan, Eoin and Crooks, Richard M. (2013) Electrochemically-gated delivery of analyte bands in microfluidic devices using bipolar electrodes. Lab on a Chip - Miniaturisation for Chemistry and Biology, 13 12: 2292-2299. doi:10.1039/c3lc50321f


Author Scida, Karen
Sheridan, Eoin
Crooks, Richard M.
Title Electrochemically-gated delivery of analyte bands in microfluidic devices using bipolar electrodes
Journal name Lab on a Chip - Miniaturisation for Chemistry and Biology   Check publisher's open access policy
ISSN 1473-0197
1473-0189
Publication date 2013-06
Year available 2013
Sub-type Article (original research)
DOI 10.1039/c3lc50321f
Open Access Status DOI
Volume 13
Issue 12
Start page 2292
End page 2299
Total pages 8
Place of publication Cambridge, United Kingdom
Publisher R S C Publications
Collection year 2014
Abstract A method for controlling enrichment, separation, and delivery of analytes into different secondary microchannels using simple microfluidic architecture is described. The approach, which is based on bipolar electrochemistry, requires only easily fabricated electrodes and a low-voltage DC power supply: no pumps or valves are necessary. Upon application of a voltage between two driving electrodes, passive bipolar electrodes (BPEs) are activated that result in formation of a local electric field gradient. This gradient leads to separation and enrichment of a pair of fluorescent analytes within a primary microfluidic channel. Subsequently, other passive BPEs can be activated to deliver the enriched tracers to separate secondary microchannels. The principles and performance underpinning the method are described.
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: School of Mathematics and Physics
Non HERDC
 
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Created: Thu, 28 Nov 2013, 16:04:54 EST by System User on behalf of School of Mathematics & Physics