Influence of dopamine on healthy adult new word learning and implications for pharmacotherapy in Aphasia

Copland, David, Mahoney, Jeff, Shellshear, Leanne, MacDonald, Anna, Whiting, Emma, Nathan, Pradeep and Silburn, Peter (2012). Influence of dopamine on healthy adult new word learning and implications for pharmacotherapy in Aphasia. In: 13th International Science of Aphasia Conference. Proceedings. 13th International Science of Aphasia Conference 2012, Groningen, Netherlands, (98-99). 7-12 September, 2012.


Author Copland, David
Mahoney, Jeff
Shellshear, Leanne
MacDonald, Anna
Whiting, Emma
Nathan, Pradeep
Silburn, Peter
Title of paper Influence of dopamine on healthy adult new word learning and implications for pharmacotherapy in Aphasia
Conference name 13th International Science of Aphasia Conference 2012
Conference location Groningen, Netherlands
Conference dates 7-12 September, 2012
Proceedings title 13th International Science of Aphasia Conference. Proceedings
Journal name Stem-, Spraak- en Taalpathologie
Place of Publication Leiden, Netherlands
Publisher Swets & Zeitlinger
Publication Year 2012
Sub-type Other
Open Access Status Link (no DOI)
ISSN 0924-7025
Volume 17
Issue Supp. 2
Start page 98
End page 99
Total pages 2
Language eng
Formatted Abstract/Summary
It has been proposed that aphasia treatment outcomes (including treatment of word production impairments) can be boosted by pairing a pharmacological agent with behavioural therapy after stroke. However, results have been mixed and progress in this field has been limited. One key obstacle in exploring whether pharmacotherapy in aphasia is worth pursuing is the lack of fundamental knowledge regarding how pharmacological agents modulate relevant aspects of language in healthy individuals. Based on the concept that new word learning in healthy individuals may be relevant to language treatment in aphasia (particularly relating to word retrieval), and knowledge that dopamine can modulate brain regions implicated in new word learning (e.g. hippocampus, prefrontal cortex), the aim of this study was to examine whether levodopa (a dopamine precursor) boosted new word learning in healthy adults over one week of training...
Subjects 2733 Otorhinolaryngology
1203 Design Practice and Management
3310 Linguistics and Language
3616 Speech and Hearing
3204 Developmental and Educational Psychology
Q-Index Code EX
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Conference Paper
Collection: Institute for Molecular Bioscience - Publications
 
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