Treatment of pulmonary exacerbations in cystic fibrosis

Smith, Daniel J., Reid, David W. and Bell, Scott C. (2011) Treatment of pulmonary exacerbations in cystic fibrosis. Therapy, 8 6: 623-643. doi:10.2217/thy.11.77


Author Smith, Daniel J.
Reid, David W.
Bell, Scott C.
Title Treatment of pulmonary exacerbations in cystic fibrosis
Journal name Therapy   Check publisher's open access policy
ISSN 1475-0708
1744-831X
Publication date 2011-11
Sub-type Article (original research)
DOI 10.2217/thy.11.77
Open Access Status
Volume 8
Issue 6
Start page 623
End page 643
Total pages 21
Place of publication London, United Kingdom
Publisher Future Medicine
Language eng
Subject 2736 Pharmacology (medical)
2700 Medicine
Formatted abstract
People with the genetic condition cystic fibrosis suffer repeated respiratory tract infections from an early age, which are often superseded by chronic airway infection, with resultant progressive loss of lung function and premature death from respiratory failure. Acute pulmonary exacerbations contribute to diminished quality of life, reduced lung function, morbidity and mortality in cystic fibrosis, and remain a major obstacle to improving long term outcomes. This article discusses current diagnostic and therapeutic strategies employed in the treatment of pulmonary exacerbations, with a focus on critical appraisal of the evidence based on which strategies are founded. Areas of uncertainty are highlighted and current and potential future research directions are discussed.
Keyword Antibiotics
Cystic fibrosis
Definition
Etiology
Infection
Treatment
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Queensland Children's Medical Research Institute Publications
School of Medicine Publications
 
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