Periodic mesoporous organosilicas with controlled pore symmetries for peptides enrichment

Liu, Fang, Yuan, Pei, Wan, Jing Jing, Qian, Kun, Wei, Guang Feng, Yang, Jie, Liu, Bao Hong, Wang, Yun Hua and Yu, Cheng Zhong (2011) Periodic mesoporous organosilicas with controlled pore symmetries for peptides enrichment. Journal of Nanoscience and Nanotechnology, 11 6: 5215-5222. doi:10.1166/jnn.2011.4127


Author Liu, Fang
Yuan, Pei
Wan, Jing Jing
Qian, Kun
Wei, Guang Feng
Yang, Jie
Liu, Bao Hong
Wang, Yun Hua
Yu, Cheng Zhong
Title Periodic mesoporous organosilicas with controlled pore symmetries for peptides enrichment
Journal name Journal of Nanoscience and Nanotechnology   Check publisher's open access policy
ISSN 1533-4880
1533-4899
Publication date 2011
Year available 2011
Sub-type Article (original research)
DOI 10.1166/jnn.2011.4127
Volume 11
Issue 6
Start page 5215
End page 5222
Total pages 8
Place of publication Valencia, CA United States
Publisher American Scientific Publishers
Collection year 2012
Language eng
Subject 3104 Condensed Matter Physics
1600 Chemistry
2500 Materials Science
1502 Banking, Finance and Investment
2204 Religion and Religious Studies
Abstract Periodic mesoporous organosilicas (PMOs) with controlled structures have been synthesized by using cetyltrimethylammonium bromide (CTAB) and sodium perfluorooctanoate (PFONa) as cotemplates, 1,2-bis (triethoxysilyl)ethane (BTEE) as an organosilica precursor. By increasing the weight ratio of PFONa/CTAB, a structure transformation from a cubic (Pm-3n) to a two-dimensional hexagonal (p6m) mesostructure and then to multilamellar vesicles can be observed. The cubic and hexagonal samples have similar particle size (200-750 nm), pore size (2.6 and 2.8 nm, respectively), total pore volume (̃0.7 cm 3/g), and surface area (̃900 m 2/g), providing ideal candidates to study the peptide enrichment performance influenced simply by pore symmetries. Matrix-assisted laser desorption ionization time-of-flight mass spectroscopy (MALDI-TOF MS) analysis indicates that PMO with a cubic (Pm-3n) structure is more effective in small molecular weight peptides enrichment compared with PMO with a hexagonal structure, showing the importance of mesostructural control for targeted applications. The phenomena can be attributed to the cage-type structure of the Pm-3n symmetry, which possesses cages with a relatively larger pore size and connectivity with a relatively smaller size. It is suggested that the pore entrances with small size are responsible for entrapping small molecular weight peptides. Our study may shed light on the designed synthesis of functional porous materials with controlled structures and enhanced performance in peptides enrichment. Copyright
Keyword MALDI-TOF MS
Mesostructure transformation
Peptides enrichment
Periodic mesoporous organosilicas
Self-assembly
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: Australian Institute for Bioengineering and Nanotechnology Publications
 
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