The tissue residue approach for toxicity assessment: Findings and critical reviews from a society of environmental toxicology and chemistry pellston workshop

Meador, James P., Adams, William J., Escher, Beate I., McCarty, Lynn S., McElroy, Anne E. and Sappingtonyy, Keith G. (2011) The tissue residue approach for toxicity assessment: Findings and critical reviews from a society of environmental toxicology and chemistry pellston workshop. Integrated Environmental Assessment and Management, 7 1: 2-6. doi:10.1002/ieam.133


Author Meador, James P.
Adams, William J.
Escher, Beate I.
McCarty, Lynn S.
McElroy, Anne E.
Sappingtonyy, Keith G.
Title The tissue residue approach for toxicity assessment: Findings and critical reviews from a society of environmental toxicology and chemistry pellston workshop
Journal name Integrated Environmental Assessment and Management   Check publisher's open access policy
ISSN 1551-3777
1551-3793
Publication date 2011
Year available 2011
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1002/ieam.133
Volume 7
Issue 1
Start page 2
End page 6
Total pages 5
Place of publication Pensacola, FL United States
Publisher Society of Environmental Toxicology and Chemistry
Collection year 2012
Language eng
Subject 2300 Environmental Science
3305 Geography, Planning and Development
Abstract Over the past few years, the "critical body residue" approach for assessing toxicity based on bioaccumulated chemicals has evolved into a more expansive consideration of tissue residues as the dose metric when defining dose-response relationships,evaluating mixtures, developing protective guidelines, and conducting risk assessments. Hence, scientists refer to "tissue residue approach for toxicity assessment" or "tissue residue-effects approach" (TRA) when addressing ecotoxicology issues pertaining to tissue (or internal) concentrations. This introduction provides an overview of a SETAC Pellston Workshop held in 2007 to review the state of the science for using tissue residues as the dose metric in environmental toxicology. The key findings of the workshop are presented, along with recommendations for research to enhance understanding of toxic responses within and between species, and to advance the use of the TRA in assessment and management of chemicals in the environment.
Keyword Critical review
Pellston workshop
Tissue residue toxicity
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collection: National Research Centre for Environmental Toxicology Publications
 
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