Contemporary management of infected total knee replacement

Tetsworth, Kevin and Dennis, Jodi (2008) Contemporary management of infected total knee replacement. Current Opinion in Orthopaedics, 19 1: 75-79. doi:10.1097/BCO.0b013e3282f2d0d8

Author Tetsworth, Kevin
Dennis, Jodi
Title Contemporary management of infected total knee replacement
Journal name Current Opinion in Orthopaedics   Check publisher's open access policy
ISSN 1041-9918
Publication date 2008
Year available 2008
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1097/BCO.0b013e3282f2d0d8
Open Access Status
Volume 19
Issue 1
Start page 75
End page 79
Total pages 5
Place of publication Philadelphia, PA United States
Publisher Lippincott Williams and Wilkins
Collection year 2009
Language eng
Subject 2746 Surgery
Abstract PURPOSE OF REVIEW: Deep infection following knee arthroplasty is unquestionably a major complication, with potentially devastating consequences. There is a risk of considerable morbidity, the cost of treatment can be high, and the loss of some function is possible even if the infection is successfully controlled. The large number of recent publications devoted to this problem is a testament to its clinical significance. RECENT FINDINGS: The two-stage approach utilizing antibiotic impregnated polymethyl methacrylate spacers has significant advantages when considering exchange arthroplasty. Articulating antibiotic polymethyl methacrylate spacers have become a popular method for staged management of infected total knee replacement. Not only do these spacers significantly improve patient mobility and comfort between stages, but their use also potentially facilitates subsequent reimplantation. SUMMARY: Successful management involves selection of treatment alternatives based on specific criteria. The responsible pathogen, the patients' immunologic status, the chronicity of infection, and the stability of the implant must all be carefully considered. When all of these criteria are favorable, retention of the prosthetic components may be considered, but when any of these criteria are unfavorable retention of the components is more likely to result in treatment failure. For deep infection of more than 3 weeks' duration most expert surgeons recommend a staged approach to management.
Keyword Antibiotic spacers
Total knee replacement
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collection: School of Medicine Publications
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