Back-scatter based whispering gallery mode sensing

Knittel, Joachim, Swaim, Jon D., McAuslan, David L., Brawley, George A. and Bowen, Warwick P. (2013) Back-scatter based whispering gallery mode sensing. Scientific Reports, 3 . doi:10.1038/srep02974

Author Knittel, Joachim
Swaim, Jon D.
McAuslan, David L.
Brawley, George A.
Bowen, Warwick P.
Title Back-scatter based whispering gallery mode sensing
Journal name Scientific Reports   Check publisher's open access policy
ISSN 2045-2322
Publication date 2013-10
Year available 2013
Sub-type Article (original research)
DOI 10.1038/srep02974
Open Access Status DOI
Volume 3
Total pages 5
Place of publication London, United Kingdom
Publisher Nature Publishing Group
Collection year 2014
Language eng
Formatted abstract
 Whispering gallery mode biosensors allow selective unlabelled detection of single proteins and, combined with quantum limited sensitivity, the possibility for noninvasive real-time observation of motor molecule motion. However, to date technical noise sources, most particularly low frequency laser noise, have constrained such applications. Here we introduce a new technique for whispering gallery mode sensing based on direct detection of back-scattered light. This experimentally straightforward technique is immune to frequency noise in principle, and further, acts to suppress thermorefractive noise. We demonstrate 27 dB of frequency noise suppression, eliminating frequency noise as a source of sensitivity degradation and
allowing an absolute frequency shift sensitivity of 76 kHz. Our results open a new pathway towards single molecule biophysics experiments and ultrasensitive biosensors.
Keyword Optical Microcavities
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: School of Mathematics and Physics
Official 2014 Collection
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Citation counts: TR Web of Science Citation Count  Cited 17 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 21 times in Scopus Article | Citations
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