Biomimetic silver-containing colloids of poly(2-methacryloyloxyethyl phosphorylcholine) and their film-formation properties

Fuchs, Adrian V., Walter, Constanze, Landfester, Katharina and Ziener, Ulrich (2012) Biomimetic silver-containing colloids of poly(2-methacryloyloxyethyl phosphorylcholine) and their film-formation properties. Langmuir, 28 11: 4974-4983. doi:10.1021/la204673z


Author Fuchs, Adrian V.
Walter, Constanze
Landfester, Katharina
Ziener, Ulrich
Title Biomimetic silver-containing colloids of poly(2-methacryloyloxyethyl phosphorylcholine) and their film-formation properties
Journal name Langmuir   Check publisher's open access policy
ISSN 0743-7463
1520-5827
Publication date 2012-03-20
Sub-type Article (original research)
DOI 10.1021/la204673z
Volume 28
Issue 11
Start page 4974
End page 4983
Total pages 10
Place of publication Washington, DC, United States
Publisher American Chemical Society
Language eng
Subject 1603 Demography
3104 Condensed Matter Physics
3110 Surfaces and Interfaces
2500 Materials Science
1607 Social Work
Formatted abstract
The synthesis of stable dispersions of hybrid colloids comprising copolymers of biocompatible 2-hydroxyethyl methacrylate (HEMA) and zwitterionic, biomimetic 2-methacryloyloxyethyl phosphorylcholine (MPC) incorporating antibacterial AgBF4 by inverse miniemulsion is described. The prepared hybrid colloids were designed to provide both antibacterial and antifouling properties for the formation of interesting, multifunctional films. The obtained particles had sizes in the range of 130-160 nm with two different weight ratios of MPC to HEMA (1:10 and 2:5) and AgBF4 contents between 0% and 15%. The silver salt takes on the role of the lipophobe in stabilizing the miniemulsion droplets against Ostwald ripening and is reduced after polymerization to Ag nanoparticles by gaseous hydrazine. Subsequently, the hybrid particles are transformed into smooth and stable films with thicknesses between 145 and 225 nm by simple drop casting and solvent annealing. The dispersions and films were thoroughly characterized by DLS, TEM, SEM, EDX, TGA, UV-vis spectroscopy, ICP-OES, XRD, AFM, and contact angle measurements. After immersion into water, the films did not show detectable leakage of silver, so they could be employed as dual-functional antifouling and antibacterial coatings.
Keyword 2-hydroxyethyl methacrylate
Polymer
Nanoparticles
Hydrogels
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: Australian Institute for Bioengineering and Nanotechnology Publications
 
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Created: Wed, 13 Nov 2013, 21:46:38 EST by Adrian Fuchs on behalf of Aust Institute for Bioengineering & Nanotechnology