An ABC pleiotropic drug resistance transporter of Fusarium graminearum with a role in crown and root diseases of wheat

Gardiner, Donald M., Stephens, Amber E., Munn, Alan L. and Manners, John M. (2013) An ABC pleiotropic drug resistance transporter of Fusarium graminearum with a role in crown and root diseases of wheat. FEMS Microbiology Letters, 348 1: 36-45. doi:10.1111/1574-6968.12240


Author Gardiner, Donald M.
Stephens, Amber E.
Munn, Alan L.
Manners, John M.
Title An ABC pleiotropic drug resistance transporter of Fusarium graminearum with a role in crown and root diseases of wheat
Journal name FEMS Microbiology Letters   Check publisher's open access policy
ISSN 0378-1097
1574-6968
Publication date 2013-11
Year available 2013
Sub-type Article (original research)
DOI 10.1111/1574-6968.12240
Open Access Status
Volume 348
Issue 1
Start page 36
End page 45
Total pages 10
Place of publication Chichester, West Sussex, United Kingdom
Publisher Wiley-Blackwell Publishing
Collection year 2014
Language eng
Formatted abstract
FgABC1 (FGSG_04580) is predicted to encode a pleiotropic drug resistance class ABC transporter in Fusarium graminearum, a globally important pathogen of wheat. Deletion mutants of FgABC1 showed reduced virulence towards wheat in crown and root infection assays but were unaltered in infectivity on barley. Expression of FgABC1 during head blight and crown rot disease increases during the necrotrophic phases of infection suggestive of a role for FgABC1 in late infection stages in different tissue types. Deletion of FgABC1 also led to increased sensitivity of the fungus to the antifungal compound benalaxyl in culture, but the response to known cereal defence compounds, gramine, 2-benzoxazalinone and tryptamine was unaltered. FgABC1 appears to have a role in protecting the fungus from antifungal compounds and is likely to help combat as yet unidentified wheat defence compounds during disease development.
Keyword Fusarium head blight
Fusarium root rot
Fusarium crown rot
Boa
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Published under Research Letter

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2014 Collection
Institute for Molecular Bioscience - Publications
 
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