Cardiopulmonary exercise testing in the assessment of pulmonary hypertension

Arena, Ross, Guazzi, Marco, Myers, Jonathan, Grinnen, Daniel, Forman, Daniel E. and Lavie, Carl J. (2011) Cardiopulmonary exercise testing in the assessment of pulmonary hypertension. Expert Review of Respiratory Medicine, 5 2: 281-293. doi:10.1586/ERS.11.4


Author Arena, Ross
Guazzi, Marco
Myers, Jonathan
Grinnen, Daniel
Forman, Daniel E.
Lavie, Carl J.
Title Cardiopulmonary exercise testing in the assessment of pulmonary hypertension
Journal name Expert Review of Respiratory Medicine   Check publisher's open access policy
ISSN 1747-6348
1747-6356
Publication date 2011-04
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1586/ERS.11.4
Open Access Status
Volume 5
Issue 2
Start page 281
End page 293
Total pages 13
Place of publication London United Kingdom
Publisher Expert Reviews
Language eng
Formatted abstract
 The assessment of patients with suspected or confirmed pulmonary arterial hypertension (PAH) and secondary pulmonary hypertension (PH) continues to evolve and, in recent years, evidence demonstrating that cardiopulmonary exercise testing (CPX) provides valuable information has grown at an impressive rate. The key premise supporting the use of CPX is that certain variables obtained provide insight into the degree of ventilation/perfusion mismatching secondary to altered pulmonary hemodynamics. In this article, we discuss the pathophysiology of PAH and secondary PH and its impact on cardiac function, review the clinical presentation of patients with elevated pulmonary pressures and outline a case for the use of CPX as an integral assessment technique, discuss CPX technology and testing procedures, and review the current state of available evidence and provide clinical recommendations for CPX in the setting of known or suspected PAH and secondary PH.
Keyword Aerobic capacity
Carbon dioxide production
Diagnosis
Minute ventilation
Prognosis
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collection: School of Medicine Publications
 
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