Pigment dispersing factor

Temmerman, Liesbet, Meelkop, Ellen and Schoofs, Liliane (2013). Pigment dispersing factor. In Abba J. Kastin (Ed.), Handbook of biologically active peptides 2nd ed. (pp. 298-303) Amsterdam, Netherlands: Academic Press/Elsevier. doi:10.1016/B978-0-12-385095-9.00041-5

Author Temmerman, Liesbet
Meelkop, Ellen
Schoofs, Liliane
Title of chapter Pigment dispersing factor
Title of book Handbook of biologically active peptides
Place of Publication Amsterdam, Netherlands
Publisher Academic Press/Elsevier
Publication Year 2013
Sub-type Chapter in textbook
DOI 10.1016/B978-0-12-385095-9.00041-5
Year available 2013
Edition 2nd
ISBN 9780123850959
Editor Abba J. Kastin
Chapter number 41
Start page 298
End page 303
Total pages 6
Total chapters 260
Collection year 2014
Language eng
Abstract/Summary Pigment-dispersing hormones (PDHs) and pigment-dispersing factors (PDFs) make up a conserved family of signaling molecules thus far only identified from invertebrate sources. They all act on their respective G-protein-coupled receptors and can act both as neurotransmitters and neurohormones. Although PDF receptors are homologs of the vertebrate VPAC2 receptor, PDF sequences have never been found in vertebrates and only a functional homology to VIP has been described. In all invertebrate PDF systems studied, a clear role in the modulation of and response to environmental signals has been described. In crustaceans, PDH is an activator of rapid pigment dispersion in response to bright light. Insect PDFs, and possibly crustacean PDH, are of crucial importance to the endogenous biological clock that keeps track of the day/night rhythm. In nematodes, PDFs exert an overt role in the regulation of locomotion. This chapter summarizes the different invertebrate PDH-like signaling systems.
Q-Index Code BX
Q-Index Status Provisional Code
Institutional Status UQ
Additional Notes Section IV: Invertebrate Peptides

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