Genomic regions associated with fertility traits in male and female cattle: Advances from microsatellites to high-density chips and beyond

Fortes, Marina R. S., DeAtley, Kasey L., Lehnert, Sigrid A., Burns, Brian M., Reverter, Antonio, Hawken, Rachel J., Boe-Hansen, Gry, Moore, Stephen S. and Thomas, Milton G. (2013) Genomic regions associated with fertility traits in male and female cattle: Advances from microsatellites to high-density chips and beyond. Animal Reproduction Science, 141 1-2: 1-19. doi:10.1016/j.anireprosci.2013.07.002


Author Fortes, Marina R. S.
DeAtley, Kasey L.
Lehnert, Sigrid A.
Burns, Brian M.
Reverter, Antonio
Hawken, Rachel J.
Boe-Hansen, Gry
Moore, Stephen S.
Thomas, Milton G.
Title Genomic regions associated with fertility traits in male and female cattle: Advances from microsatellites to high-density chips and beyond
Journal name Animal Reproduction Science   Check publisher's open access policy
ISSN 0378-4320
1873-2232
Publication date 2013-09
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1016/j.anireprosci.2013.07.002
Volume 141
Issue 1-2
Start page 1
End page 19
Total pages 19
Place of publication Amsterdam, Netherlands
Publisher Elsevier
Collection year 2014
Language eng
Abstract A current challenge in genetic improvement of cattle is to identify genomic selection strategies that could work across breeds. Breed differences, scarcity of data, and lack of quantitative trait loci (QTL) validation contribute to this challenge. We conducted a review of the literature to identify QTL, markers, and candidate genes that are associated with fertility across breeds to arrive at an integrated view of bovine fertility genomics and to guide the direction of future studies. This review considers both male and female fertility traits as these are economically relevant for all breeds and production systems. Regions associated with fertility traits were found in each of the 30 bovine chromosomes, confirming the complexity of these polygenic traits. Across breeds, regions on chromosomes 1, 5, 14, and 16 were associated with female reproductive traits. The X chromosome was associated with male reproductive traits in both dairy and beef bulls. It has recently been proposed that a Y chromosome anomaly may be involved in infertility in cows. Knowledge of these QTL may assist discovery of causative mutations and has the potential to improve the accuracy of genomic selection, especially across breeds of cattle.
Keyword Quantitative trait loci
Reproductive traits
Bovine
Sex chromosomes
Genetic markers
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: Queensland Alliance for Agriculture and Food Innovation
Official 2014 Collection
School of Veterinary Science Publications
 
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Citation counts: TR Web of Science Citation Count  Cited 11 times in Thomson Reuters Web of Science Article | Citations
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