Challenges for standardization of Clostridium difficile typing methods

Huber, Charlotte A., Foster, Niki F., Riley, Thomas V. and Paterson, David L. (2013) Challenges for standardization of Clostridium difficile typing methods. Journal of Clinical Microbiology, 51 9: 2810-2814. doi:10.1128/JCM.00143-13

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Author Huber, Charlotte A.
Foster, Niki F.
Riley, Thomas V.
Paterson, David L.
Title Challenges for standardization of Clostridium difficile typing methods
Formatted title
Challenges for standardization of Clostridium difficile typing methods
Journal name Journal of Clinical Microbiology   Check publisher's open access policy
ISSN 0095-1137
1098-660X
Publication date 2013-09
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1128/JCM.00143-13
Open Access Status File (Publisher version)
Volume 51
Issue 9
Start page 2810
End page 2814
Total pages 5
Place of publication Washington, DC, United States
Publisher American Society for Microbiology
Collection year 2014
Language eng
Formatted abstract
Typing of Clostridium difficile facilitates understanding of the epidemiology of the infection. Some evaluations have shown that certain strain types (for example, ribotype 027) are more virulent than others and are associated with worse clinical outcomes. Although restriction endonuclease analysis (REA) and pulsed-field gel electrophoresis have been widely used in the past, PCR ribotyping is the current method of choice for typing of C. difficile. However, global standardization of ribotyping results is urgently needed. Whole-genome sequencing of C. difficile has the potential to provide even greater epidemiologic information than ribotyping.
Q-Index Code CX
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: UQ Centre for Clinical Research Publications
Non HERDC
 
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Citation counts: TR Web of Science Citation Count  Cited 15 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 18 times in Scopus Article | Citations
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Created: Sun, 29 Sep 2013, 00:22:57 EST by System User on behalf of UQ Centre for Clinical Research