Reference ranges for mexican preschool-aged children using the forced oscillation technique

Shackleton, Claire, Barraza-Villarreal, Albino, Chen, Linping, Gangell, Catherine L., Romieu, Isabelle and Sly, Peter D. (2013) Reference ranges for mexican preschool-aged children using the forced oscillation technique. Archivos De Bronconeumologia, 49 8: 326-329. doi:10.1016/j.arbres.2013.01.014

Author Shackleton, Claire
Barraza-Villarreal, Albino
Chen, Linping
Gangell, Catherine L.
Romieu, Isabelle
Sly, Peter D.
Title Reference ranges for mexican preschool-aged children using the forced oscillation technique
Journal name Archivos De Bronconeumologia   Check publisher's open access policy
ISSN 0300-2896
Publication date 2013-08
Sub-type Article (original research)
DOI 10.1016/j.arbres.2013.01.014
Volume 49
Issue 8
Start page 326
End page 329
Total pages 4
Place of publication Barcelona, Spain
Publisher Elsevier
Collection year 2014
Language spa
Formatted abstract
Introduction: Recently, multi-ethnic reference ranges for spirometry have been created for use worldwide. In comparison, forced oscillation technique (FOT) reference values are limited to specific equipment and study populations, with current FOT reference ranges created in a Caucasian population. We aimed to develop FOT reference ranges for preschool-aged Mexican children and to compare these with current FOT reference ranges.

Patients and methods: Respiratory resistance (Rrs) and reactance (Xrs) was measured in healthy Mexican children three to five years of age using commercial FOT equipment. The relationship between height and Rrs and Xrs was determined using regression analyses, taking into account age, weight, sex, and exposure to tobacco smoke. Reference equations were calculated for the Mexican children and Z-scores determined for Rrs and Xrs at 6 and 8. Hz. A paired t-test assessed the difference in Z-scores between the Australian reference values and those created for the Mexican cohort.

Results: FOT was successfully measured in 584. children. Height was a significant predictor of Rrs and Xrs at 6 and 8. Hz (P< .05). Z-scores calculated using the Australian reference equations overestimated lung function in Mexican children for both Rrs and Xrs at 6 and 8. Hz (P< .001).

Conclusion: The development of FOT reference ranges specific to Mexican preschool-aged children will allow for the correct interpretation of FOT measurements. This study also showed that current FOT reference ranges overestimate lung function in Mexican children. Highlighting, the importance of using ethnic appropriate reference ranges for interpreting lung function.
Keyword Forced oscillation technique
Reference ranges
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2014 Collection
Queensland Children's Medical Research Institute Publications
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