The outcome of isolated primary fetal hydrothorax: a 10-year review from a tertiary center

Petersen, Scott, Kaur, Ravinderjit, Thomas, Joseph T., Cincotta, Robert and Gardener, Glenn (2013) The outcome of isolated primary fetal hydrothorax: a 10-year review from a tertiary center. Fetal Diagnosis and Therapy, 34 2: 69-76. doi:10.1159/000351855

Author Petersen, Scott
Kaur, Ravinderjit
Thomas, Joseph T.
Cincotta, Robert
Gardener, Glenn
Title The outcome of isolated primary fetal hydrothorax: a 10-year review from a tertiary center
Journal name Fetal Diagnosis and Therapy   Check publisher's open access policy
ISSN 1015-3837
Publication date 2013-08
Year available 2013
Sub-type Article (original research)
DOI 10.1159/000351855
Open Access Status
Volume 34
Issue 2
Start page 69
End page 76
Total pages 8
Place of publication Basel, Switzerland
Publisher S. Karger AG
Collection year 2014
Language eng
Formatted abstract
Introduction: The management of primary fetal pleural effusion remains a challenge for clinicians given the paucity of clinical information to guide practice.

Materials and Methods: A retrospective descriptive study of cases referred for management to our fetal therapy center over a 10-year period. Survival to hospital discharge was evaluated against case characteristics and prenatal intervention. For this study, we categorized the severity of the pleural effusion at diagnosis as mild, moderate or severe, and the clinical course as regression, stable or progression.

Results: Forty-five of the 103 pregnancies complicated by fetal pleural effusions during the study period were managed for primary effusions. Termination of pregnancy was requested in 6 cases. Thirty-nine pregnancies continued management, with 14 undergoing prenatal intervention. The overall survival rate to hospital discharge was 51%, including 7 survivors after prenatal intervention. The rate of survival was low if the effusion was categorized as severe at diagnosis or if there was progression of the clinical course.

Conclusions: Case characteristics at the time of diagnosis and clinical course can be used to guide patient counseling and decision-making regarding fetal therapy. Prenatal intervention may improve the chance of survival in cases with characteristics associated with a poor prognosis.
Keyword Fetal hydrothorax
Primary pleural effusion
Fetal therapy
Thoracoamniotic shunt
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Mater Research Institute-UQ (MRI-UQ)
Official 2014 Collection
School of Medicine Publications
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Citation counts: TR Web of Science Citation Count  Cited 3 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 2 times in Scopus Article | Citations
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Created: Sun, 29 Sep 2013, 00:10:15 EST by System User on behalf of Obstetrics & Gynaecology - Mater Hospital