Whole-genome sequencing reveals untapped genetic potential in Africa's indigenous cereal crop sorghum

Mace, Emma S., Tai, Shuaishuai, Gilding, Edward K., Li, Yanhong, Prentis, Peter J., Bian, Lianle, Campbell, Bradley C., Hu, Wushu, Innes, David J., Han, Xuelian, Cruickshank, Alan, Dai, Changming, Frere, Celine, Zhang, Haikuan, Hunt, Colleen H., Wang, Xianyuan, Shatte, Tracey, Wang, Miao, Su, Zhe, Li, Jun, Lin, Xiaozhen, Godwin, Ian D., Jordan, David R. and Wang, Jun (2013) Whole-genome sequencing reveals untapped genetic potential in Africa's indigenous cereal crop sorghum. Nature Communications, 4 2320.1-2320.8. doi:10.1038/ncomms3320

Author Mace, Emma S.
Tai, Shuaishuai
Gilding, Edward K.
Li, Yanhong
Prentis, Peter J.
Bian, Lianle
Campbell, Bradley C.
Hu, Wushu
Innes, David J.
Han, Xuelian
Cruickshank, Alan
Dai, Changming
Frere, Celine
Zhang, Haikuan
Hunt, Colleen H.
Wang, Xianyuan
Shatte, Tracey
Wang, Miao
Su, Zhe
Li, Jun
Lin, Xiaozhen
Godwin, Ian D.
Jordan, David R.
Wang, Jun
Title Whole-genome sequencing reveals untapped genetic potential in Africa's indigenous cereal crop sorghum
Journal name Nature Communications   Check publisher's open access policy
ISSN 2041-1723
Publication date 2013-08
Year available 2013
Sub-type Article (original research)
DOI 10.1038/ncomms3320
Open Access Status DOI
Volume 4
Start page 2320.1
End page 2320.8
Total pages 9
Place of publication London, United Kingdom
Publisher Nature Publishing Group
Collection year 2014
Language eng
Formatted abstract
Sorghum is a food and feed cereal crop adapted to heat and drought and a staple for 500 million of the world’s poorest people. Its small diploid genome and phenotypic diversity make it an ideal C4 grass model as a complement to C3 rice. Here we present high coverage (16–45 × ) resequenced genomes of 44 sorghum lines representing the primary gene pool and spanning dimensions of geographic origin, end-use and taxonomic group. We also report the first resequenced genome of S. propinquum, identifying 8 M high-quality SNPs, 1.9 M indels and specific gene loss and gain events in S. bicolor. We observe strong racial structure and a complex domestication history involving at least two distinct domestication events. These assembled genomes enable the leveraging of existing cereal functional genomics data against the novel diversity available in sorghum, providing an unmatched resource for the genetic improvement of sorghum and other grass species.
Keyword Bicolor L. Moench
Linkage Disequilibrium
Wide Patterns
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: School of Agriculture and Food Sciences
Official 2014 Collection
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 53 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 73 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Sun, 22 Sep 2013, 00:13:35 EST by System User on behalf of School of Agriculture and Food Sciences