Plasma-sprayed hydroxyapatite coating on carbon/carbon composite scaffolds for bone tissue engineering and related tests in vivo

Cao, Ning, Dong, Jianwen, Wang, Qiangxiu, Ma, Quansheng, Wang, Feng, Chen, Huaying, Xue, Chengqian and Li, Musen (2010) Plasma-sprayed hydroxyapatite coating on carbon/carbon composite scaffolds for bone tissue engineering and related tests in vivo. Journal of Biomedical Materials Research Part A, 92A 3: 1019-1027. doi:10.1002/jbm.a.32424


Author Cao, Ning
Dong, Jianwen
Wang, Qiangxiu
Ma, Quansheng
Wang, Feng
Chen, Huaying
Xue, Chengqian
Li, Musen
Title Plasma-sprayed hydroxyapatite coating on carbon/carbon composite scaffolds for bone tissue engineering and related tests in vivo
Journal name Journal of Biomedical Materials Research Part A   Check publisher's open access policy
ISSN 1549-3296
1552-4965
Publication date 2010-03-01
Year available 2010
Sub-type Article (original research)
DOI 10.1002/jbm.a.32424
Volume 92A
Issue 3
Start page 1019
End page 1027
Total pages 9
Place of publication Hoboken, NJ United States
Publisher John Wiley and Sons
Collection year 2011
Language eng
Formatted abstract
The bioactive hydroxyapatite (HA) coatings were successfully prepared on carbon/carbon composites (C/C) by means of sand-blasting pretreatment and plasma-spraying technology. X-ray diffraction was employed to analyze the phase constitute of the coatings. Meanwhile, the bond strength between the HA coatings and C/C substrates was determined via shear test. Experimental results show that the coatings constitute HA, CaO, and other amorphous phosphates. The post heat treatment could effectively increase crystallization and purity of the coatings. Through observation and analysis by electron microprobe and scanning electron microscopy, it is concluded that the bond strength of the plasma-sprayed HA coatings on C/C is mainly determined by the interface structure and can be further improved by the post heat treatment. Meanwhile, the implantation in vivo was carried out in hybrid goats. The histological observation revealed that the osteoplaque gradually grew on the surface of the HA coatings and the pure C/C surface was covered by the fibrous tissues. No inflammation symptoms were found in the bone tissue around the implants.
Keyword Hydroxyapatite
Coating
Interface
Histology
Carbon Carbon Composite
Orthopedic Implants
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: Australian Institute for Bioengineering and Nanotechnology Publications
 
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Created: Wed, 18 Sep 2013, 20:36:59 EST by Cathy Fouhy on behalf of Aust Institute for Bioengineering & Nanotechnology