"Click" PNIPAAm hydrogels - a comprehensive study of structure and properties

Ooi, Huey Wen, Jack, Kevin S., Peng, Hui and Whittaker, Andrew K. (2013) "Click" PNIPAAm hydrogels - a comprehensive study of structure and properties. Polymer Chemistry, 4 17: 4788-4800. doi:10.1039/c3py00653k

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Author Ooi, Huey Wen
Jack, Kevin S.
Peng, Hui
Whittaker, Andrew K.
Title "Click" PNIPAAm hydrogels - a comprehensive study of structure and properties
Journal name Polymer Chemistry   Check publisher's open access policy
ISSN 1759-9954
Publication date 2013-09
Year available 2013
Sub-type Article (original research)
DOI 10.1039/c3py00653k
Open Access Status Not Open Access
Volume 4
Issue 17
Start page 4788
End page 4800
Total pages 13
Place of publication Cambridge, United Kingdom
Publisher R S C Publications
Collection year 2014
Language eng
Abstract A detailed understanding of the structural and chemical features of hydrogels is vital when it comes to modifying and tailoring these materials into potential beneficial tools for different disciplines, such as drug delivery, membrane science, etc. However the characterization of hydrogels using conventional analytical techniques is a major challenge since they are three-dimensional crosslinked molecules of effectively infinite molecular weight. Control of the structure of networks of poly(N-isopropylacrylamide) (PNIPAAm) is especially important considering the reported sensitivity of the thermal properties of linear PNIPAAm to molecular weight and end group structure. Therefore in this work we have studied for the first time a series of telechelic PNIPAAm chains synthesized by reversible addition-fragmentation chain transfer (RAFT) polymerization and used these to prepare highly regular networks by end-linking to a tetra-acetylene crosslinker via the copper(i)-catalyzed azide-alkyne cycloaddition reaction. Detailed comments on the reaction conditions required to form hydrogels are provided. The pore structure of the hydrogels was varied by selection of the molecular weight of the PNIPAAm resulting in networks with different mesh sizes. The thermal and transport properties of the hydrogels are especially sensitive to the structure of the hydrogel and have been extensively characterized.
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

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