The regulation of urokinase plasminogen activator gene expression in macrophages

Stacey, K. J., Cassady, A. I., Nimmo, K. A., Murphy, K. M., von der Ahe, D., Pearson, D., Botteri, F., Nagamine, Y. and Hume, D. A. (1992). The regulation of urokinase plasminogen activator gene expression in macrophages. In van Furth, R. (Ed.), Mononuclear Phagocytes: Biology of Monocytes and Macrophages (pp. 233-240) Dordrecht , Netherlands: Kluwer Academic Publishers. doi:10.1007/978-94-015-8070-0


Author Stacey, K. J.
Cassady, A. I.
Nimmo, K. A.
Murphy, K. M.
von der Ahe, D.
Pearson, D.
Botteri, F.
Nagamine, Y.
Hume, D. A.
Title of chapter The regulation of urokinase plasminogen activator gene expression in macrophages
Title of book Mononuclear Phagocytes: Biology of Monocytes and Macrophages
Place of Publication Dordrecht , Netherlands
Publisher Kluwer Academic Publishers
Publication Year 1992
Sub-type Research book chapter (original research)
DOI 10.1007/978-94-015-8070-0
ISBN 9789048141715
9789401580700
Editor van Furth, R.
Chapter number 31
Start page 233
End page 240
Total pages 8
Total chapters 88
Language eng
Formatted Abstract/Summary
Urokinase plasminogen activator (uPA) is a specific serine protease which converts the zymogen plasminogen into plasmin, a protease of broad specificity. uPA has been implicated in extracellular proteolysis in numerous cellular systems involving cellular migration, tissue remodelling, or invasive growth and metastasis of tumours. In macrophages uPA is thought to be involved in cellular migration during the inflammatory response and is bound to a specific receptor on the leading edge of monocytes migrating in vitro.
Q-Index Code B1
Q-Index Status Provisional Code
Institutional Status Unknown

Document type: Book Chapter
Collection: School of Chemistry and Molecular Biosciences
 
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 2 times in Thomson Reuters Web of Science Article | Citations
Google Scholar Search Google Scholar
Created: Fri, 06 Sep 2013, 17:54:59 EST by Dr Katryn Stacey on behalf of School of Chemistry & Molecular Biosciences