Small-molecule dissection of BMP signaling

Anderson, Gregory J. and Darshan, Deepak (2008) Small-molecule dissection of BMP signaling. Nature Chemical Biology, 4 1: 15-16. doi:10.1038/nchembio0108-15


Author Anderson, Gregory J.
Darshan, Deepak
Title Small-molecule dissection of BMP signaling
Journal name Nature Chemical Biology   Check publisher's open access policy
ISSN 1552-4450
1552-4469
Publication date 2008-01
Year available 2008
Sub-type Other
DOI 10.1038/nchembio0108-15
Open Access Status
Volume 4
Issue 1
Start page 15
End page 16
Total pages 2
Place of publication London, United Kingdom
Publisher Nature Publishing Group
Collection year 2008
Language eng
Formatted abstract
Analysis of the multifunctional bone morphogenetic protein (BMP) signaling pathway has been hampered by the lack of specific reagents for discriminating downstream signaling events. A new study uses a novel zebrafish embryo screen to identify dorsomorphin, the first small-molecule inhibitor of BMP signaling, and shows its application in fields as diverse as osteogenesis, developmental patterning and iron homeostasis. 
Keyword Iron metabolism
Transduction
Expression
Q-Index Code CX
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Other
Collection: School of Medicine Publications
 
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Citation counts: TR Web of Science Citation Count  Cited 32 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 35 times in Scopus Article | Citations
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