Nanovaccines and their mode of action

Zaman, Mehfuz, Good, Michael F. and Toth, Istvan (2013) Nanovaccines and their mode of action. Methods, 60 3: 226-231. doi:10.1016/j.ymeth.2013.04.014

Author Zaman, Mehfuz
Good, Michael F.
Toth, Istvan
Title Nanovaccines and their mode of action
Journal name Methods   Check publisher's open access policy
ISSN 1046-2023
Publication date 2013-05-01
Year available 2013
Sub-type Article (original research)
DOI 10.1016/j.ymeth.2013.04.014
Volume 60
Issue 3
Start page 226
End page 231
Total pages 6
Place of publication Maryland Heights, MO, United States
Publisher Academic Press
Collection year 2014
Language eng
Abstract Nanosized particles including nanovaccines are a novel approach to the development of vaccines to combat diseases. Nanovaccines have the promise to utilize the immune system to cure infections and to prevent infections and diseases from spreading. Rational vaccine development requires an understanding of vaccine mediated stimulation of the immune system. We review here immunostimulatory properties of nanovaccines including their immunogenicity, adjuvant properties, inflammatory responses and the mechanisms of uptake and stimulation of immune cells. Examples of various nanoparticles currently being developed as vaccines are also provided.
Keyword Nanoparticles
Immune system
Antigen uptake
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2014 Collection
School of Chemistry and Molecular Biosciences
School of Pharmacy Publications
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Citation counts: TR Web of Science Citation Count  Cited 16 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 18 times in Scopus Article | Citations
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