Lateral temporal bone resection in advanced cutaneous squamous cell carcinoma: report of 35 patients

Essig, Garth F., Kitipornchai, Leon, Adams, Felicity, Zarate, Dannie, Gandhi, Mitesh, Porceddu, Sandro and Panizza, Benedict (2013) Lateral temporal bone resection in advanced cutaneous squamous cell carcinoma: report of 35 patients. Journal of Neurological Surgery, Part B: Skull Base, 74 1: 54-59. doi:10.1055/s-0032-1331021

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Author Essig, Garth F.
Kitipornchai, Leon
Adams, Felicity
Zarate, Dannie
Gandhi, Mitesh
Porceddu, Sandro
Panizza, Benedict
Title Lateral temporal bone resection in advanced cutaneous squamous cell carcinoma: report of 35 patients
Journal name Journal of Neurological Surgery, Part B: Skull Base   Check publisher's open access policy
ISSN 2193-6331
Publication date 2013-02
Year available 2012
Sub-type Article (original research)
DOI 10.1055/s-0032-1331021
Open Access Status
Volume 74
Issue 1
Start page 54
End page 59
Total pages 6
Place of publication New York, NY, United States
Publisher Thieme Medical Publishers
Collection year 2014
Language eng
Formatted abstract
Objective: To evaluate lateral temporal bone resection (LTBR) in the management of advanced cutaneous squamous cell carcinoma (SCC) with temporal bone invasion and patterns of failure.

Methods: This is a retrospective study of 35 patients undergoing lateral temporal bone resection for advanced cutaneous SCC at a tertiary care center between 1995 and 2006.

Results: The Pittsburgh tumor stage was T4 in 18 patients (51%), T3 in 5 (14%), T2 in 9 (26%), and T1 in 3 (9%). Clear margins were reported in 22 (63%) patients. Resection of the mandible and/or temporomandibular joint (TMJ) was required in 11 (31%) patients. Facial nerve involvement was seen in 10 (29%) patients. Survival outcomes at 2 and 5 years for overall survival were 72% and 49%; disease-free survival, 68% and 59%; and disease-specific survival, 79% and 62%, respectively. Pittsburgh T stage correlated significantly with disease-specific survival (p = 0.015) and margin status was significant for both disease-free survival (p = 0.0015) and disease-specific survival (p < 0.001).

Conclusions: Surgery with curative intent is justified for cutaneous SCC invading the temporal bone with extended LTBR. Margin status was a significant predictor of outcome. Surgeons should plan preoperatively to achieve clear margins by extending the LTBR with possible nerve resection.
Keyword Temporal bone
Cutaneous malignancy
Squamous cell carcinoma
Temporal bone resection
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Published online: 12 December 2012.

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2014 Collection
School of Medicine Publications
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Citation counts: TR Web of Science Citation Count  Cited 5 times in Thomson Reuters Web of Science Article | Citations
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