AlCl3 mediated unexpected migration of sulfonyl groups: regioselective synthesis of 7-sulfonyl indoles of potential pharmacological interest

Prasad, Bagineni, Adepu, Raju, Sandra, Sandhya, Rambabu, D., Krishna, G. Rama, Reddy, C. Malla, Deora, Girdhar Singh, Misra, Parimal and Pal, Manojit (2012) AlCl3 mediated unexpected migration of sulfonyl groups: regioselective synthesis of 7-sulfonyl indoles of potential pharmacological interest. Chemical Communications, 48 84: 10434-10436. doi:10.1039/c2cc35757g


Author Prasad, Bagineni
Adepu, Raju
Sandra, Sandhya
Rambabu, D.
Krishna, G. Rama
Reddy, C. Malla
Deora, Girdhar Singh
Misra, Parimal
Pal, Manojit
Title AlCl3 mediated unexpected migration of sulfonyl groups: regioselective synthesis of 7-sulfonyl indoles of potential pharmacological interest
Journal name Chemical Communications   Check publisher's open access policy
ISSN 1359-7345
1364-548X
Publication date 2012
Sub-type Article (original research)
DOI 10.1039/c2cc35757g
Open Access Status DOI
Volume 48
Issue 84
Start page 10434
End page 10436
Total pages 3
Place of publication Cambridge, United Kingdom
Publisher R S C Publications
Language eng
Formatted abstract
A conceptually new and straightforward introduction of sulfonyl groups at the C-7 position of an indole ring has been achieved via AlCl3 mediated unexpected regioselective sulfonyl group migration for N-alkyl/aryl/heteroarylsulfonyl indoles affording potential inhibitors of Mycobacterium tuberculosis H37Rv chorismate mutase.
Keyword Secreted chorismate mutase
Mycobacterium-tuberculosis
Agents
Q-Index Code C2
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Pharmacy Publications
 
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