Health-related quality of life and life satisfaction in colorectal cancer survivors: trajectories of adjustment

Dunn, Jeff, Ng, Shu Kay, Breitbart, William, Aitken, Joanne, Youl, Pip, Baade, Peter D. and Chambers, Suzanne K. (2013) Health-related quality of life and life satisfaction in colorectal cancer survivors: trajectories of adjustment. Health and Quality of Life Outcomes, 11 . doi:10.1186/1477-7525-11-46

Author Dunn, Jeff
Ng, Shu Kay
Breitbart, William
Aitken, Joanne
Youl, Pip
Baade, Peter D.
Chambers, Suzanne K.
Title Health-related quality of life and life satisfaction in colorectal cancer survivors: trajectories of adjustment
Journal name Health and Quality of Life Outcomes   Check publisher's open access policy
ISSN 1477-7525
Publication date 2013-03
Year available 2013
Sub-type Article (original research)
DOI 10.1186/1477-7525-11-46
Open Access Status DOI
Volume 11
Total pages 8
Place of publication London, United Kingdom
Publisher BioMed Central
Collection year 2014
Language eng
Formatted abstract
Background: This longitudinal study describes the five year trajectories of health-related quality of life (HR-QOL) and life satisfaction in long term colorectal cancer survivors.

Patients and methods: A population-based sample of 1966 colorectal cancer survivors were surveyed at six time points from five months to five years post-diagnosis. Predictor variables were: socio-demographic variables, optimism; cancer threat appraisal; perceived social support. Quality of life was assessed with the Functional Assessment of Cancer Therapy-Colorectal (HR-QOL); and the Satisfaction with Life Scale. Growth mixture models were applied to identify trajectory classes and their predictors.

Results: Distinct adjustment trajectories were identified for HR-QOL and life satisfaction. Lower optimism, poorer social support, a more negative cognitive appraisal, and younger age were associated with poorer life satisfaction, while survivors with less than 8 years of education had higher life satisfaction. This pattern was similar for overall HR-QOL except that educational level was not a significant predictor and later stage disease and female gender emerged as related to poorer outcomes. One in five survivors reported poorer constant HR-QOL (19.2%) and a small group had poor life satisfaction (7.2%); 26.2% reported constant high HR-QOL and 48.8% had high constant life satisfaction. Socioeconomic disadvantage and remoteness of residence uniquely predicted poorer outcomes in the colorectal cancer specific HR-QOL sub domain.

Conclusion: Although HR-QOL and subjective cognitive QOL share similar antecedents their trajectory patterns suggested they are distinct adjustment outcomes; with life satisfaction emerging as temporally stable phenomenon. Unique patterns of risk support suggest the need to account for heterogeneity in adjustment in longitudinal QOL studies with cancer survivors.
Keyword Longitudinal
Quality of life
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Article number 46

Document type: Journal Article
Sub-type: Article (original research)
Collections: UQ Centre for Clinical Research Publications
Official 2014 Collection
School of Social Science Publications
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Citation counts: TR Web of Science Citation Count  Cited 15 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 19 times in Scopus Article | Citations
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