Spatiotemporal Patterns of Japanese Encephalitis in China, 2002–2010

Wang, Li-Ya, Zhang, Wen-Yi, Ding, Fan, Hu, Wen-Biao, Soares Magalhaes, Ricardo J., Sun, Hai-Long, Li, Yi-Xing, Zou, Wen, Wang, Yong, Liu, Qi-Yong, Li, Shen-Long, Yin, Wen-Wu, Huang, Liu-Yu, Clements, Archie C. A., Bi, Peng and Li, Cheng-Yi (2013) Spatiotemporal Patterns of Japanese Encephalitis in China, 2002–2010. PLoS Neglected Tropical Diseases, 7 6: e2285.8-e2285.8. doi:10.1371/journal.pntd.0002285

Author Wang, Li-Ya
Zhang, Wen-Yi
Ding, Fan
Hu, Wen-Biao
Soares Magalhaes, Ricardo J.
Sun, Hai-Long
Li, Yi-Xing
Zou, Wen
Wang, Yong
Liu, Qi-Yong
Li, Shen-Long
Yin, Wen-Wu
Huang, Liu-Yu
Clements, Archie C. A.
Bi, Peng
Li, Cheng-Yi
Title Spatiotemporal Patterns of Japanese Encephalitis in China, 2002–2010
Journal name PLoS Neglected Tropical Diseases   Check publisher's open access policy
ISSN 1935-2727
Publication date 2013-06-20
Sub-type Article (original research)
DOI 10.1371/journal.pntd.0002285
Open Access Status DOI
Volume 7
Issue 6
Start page e2285.8
End page e2285.8
Total pages 8
Place of publication San Francisco, CA, United States
Publisher Public Library of Science
Collection year 2014
Language eng
Formatted abstract
Objective: The aim of the study is to examine the spatiotemporal pattern of Japanese Encephalitis (JE) in mainland China during 2002–2010. Specific objectives of the study were to quantify the temporal variation in incidence of JE cases, to determine if clustering of JE cases exists, to detect high risk spatiotemporal clusters of JE cases and to provide evidence-based preventive suggestions to relevant stakeholders.

Methods: Monthly JE cases at the county level in mainland China during 2002–2010 were obtained from the China Information System for Diseases Control and Prevention (CISDCP). For the purpose of the analysis, JE case counts for nine years were aggregated into four temporal periods (2002; 2003–2005; 2006; and 2007–2010). Local Indicators of Spatial Association and spatial scan statistics were performed to detect and evaluate local high risk space-time clusters.

Results: JE incidence showed a decreasing trend from 2002 to 2005 but peaked in 2006, then fluctuated over the study period. Spatial cluster analysis detected high value clusters, mainly located in Southwestern China. Similarly, we identified a primary spatiotemporal cluster of JE in Southwestern China between July and August, with the geographical range of JE transmission increasing over the past years.

Conclusion: JE in China is geographically clustered and its spatial extent dynamically changed during the last nine years in mainland China. This indicates that risk factors for JE infection are likely to be spatially heterogeneous. The results may assist national and local health authorities in the development/refinement of a better preventive strategy and increase the effectiveness of public health interventions against JE transmission.
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Article number e2285

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2014 Collection
School of Public Health Publications
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Citation counts: TR Web of Science Citation Count  Cited 13 times in Thomson Reuters Web of Science Article | Citations
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Created: Fri, 21 Jun 2013, 16:31:38 EST by Dr Ricardo J. Soares Magalhães on behalf of School of Public Health