The charms and challenges of antiretroviral therapy in Uganda: the DART experience

Nyanzi-Wakholi, Barbara, Lara, Antonieta Medina, Munderi, Paula and Gilks, Charles (2012) The charms and challenges of antiretroviral therapy in Uganda: the DART experience. Aids Care, 24 2: 137-142. doi:10.1080/09540121.2011.596518

Author Nyanzi-Wakholi, Barbara
Lara, Antonieta Medina
Munderi, Paula
Gilks, Charles
Title The charms and challenges of antiretroviral therapy in Uganda: the DART experience
Journal name Aids Care   Check publisher's open access policy
ISSN 0954-0121
Publication date 2012-01
Year available 2012
Sub-type Article (original research)
DOI 10.1080/09540121.2011.596518
Open Access Status
Volume 24
Issue 2
Start page 137
End page 142
Total pages 6
Place of publication Abingdon, Oxon, United Kingdom
Publisher Routledge
Collection year 2012
Language eng
Formatted abstract
 Antiretroviral therapy (ART) improves the quality of life of people living with HIV/AIDS. However, adherence remains a challenge. A total of eight focus group discussions (FGD) were conducted with participants from a randomised controlled trial that monitored strategies for managing ART in African adults: Development of Antiretroviral Therapy. All FGD participants had received ART for at least one year. Perceived benefits of ART were key motivators for adherence. These benefits included improved physical health, restored self-esteem, acceptance in the community and hope for a longer and healthier life and reduced fear of HIV/AIDS-related death. Barriers to adherence included a high pill burden, ART side effects and socio-economic constraints, including lack of food and safe water for taking the pills. Visible ART side effects and involvement in an exclusively HIV/AIDS clinic could expose their HIV status, thus exacerbating stigma. Gender and socio-economic differences were found in the variety of strategies employed to ensure adherence. ART was perceived as improving the overall quality of life of recipients; however, it is crucial for ART programmes to be gender and socio-economic cognizant in order to enhance adherence to a lifelong therapy.
Keyword Adherence
Antiretroviral Treatment
Focus group discussions
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Public Health Publications
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Citation counts: TR Web of Science Citation Count  Cited 6 times in Thomson Reuters Web of Science Article | Citations
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