Moyamoya disease in pregnancy: maintenance of maternal blood pressure

Barrett, Helen L., Lust, Karin, Fagermo, Narelle, Callaway, Leonie K. and Minuzzo, Lee (2012) Moyamoya disease in pregnancy: maintenance of maternal blood pressure. Obstetric Medicine, 5 1: 32-34. doi:10.1258/om.2011.110046

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Author Barrett, Helen L.
Lust, Karin
Fagermo, Narelle
Callaway, Leonie K.
Minuzzo, Lee
Title Moyamoya disease in pregnancy: maintenance of maternal blood pressure
Journal name Obstetric Medicine   Check publisher's open access policy
ISSN 1753-495X
Publication date 2012-03
Sub-type Article (original research)
DOI 10.1258/om.2011.110046
Volume 5
Issue 1
Start page 32
End page 34
Total pages 3
Place of publication London, United Kingdom
Publisher Sage Publications
Collection year 2013
Language eng
Abstract Moyamoya disease is a rare cerebrovascular occlusive disorder characterized by stenosis in the circle of Willis with the development of a compensatory circulation. It has been associated with significant morbidity in pregnancy including intracranial haemorrhage, ischaemic stroke and epilepsy. We present the case of a 26-year-old woman with a previous diagnosis of moyamoya vasculopathy with bilateral superficial temporal to middle cerebral artery bypass grafting. During the second trimester, she developed significant neurological symptoms related to postural hypotension in the presence of a stenosis of the right-sided graft. The hypotension was treated with fludrocortisone therapy with improvement in blood pressure and symptoms. Moyamoya vasculopathy poses unique challenges to obstetric care. This is the first report of use of fludrocortisone for maintenance of blood pressure during pregnancy in this condition.
Keyword Moyamoya disease
Cerebral artery bypass grafting
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Published online before print 8 December 2011.

Document type: Journal Article
Sub-type: Article (original research)
Collections: UQ Centre for Clinical Research Publications
Official 2013 Collection
School of Medicine Publications
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Created: Tue, 14 May 2013, 15:23:46 EST by Leonie Callaway on behalf of Royal Brisbane Clinical School