Charting a seven-year trajectory of language outcomes for a child with galactosemia

Lewis, Fiona M., Coman, David J., Syrmis, Maryann, Kilcoyne, Sarah and Murdoch, Bruce E. (2013) Charting a seven-year trajectory of language outcomes for a child with galactosemia. Journal of Developmental and Behavioral Pediatrics, 34 6: 414-418. doi:10.1097/DBP.0b013e31829a7be1

Author Lewis, Fiona M.
Coman, David J.
Syrmis, Maryann
Kilcoyne, Sarah
Murdoch, Bruce E.
Title Charting a seven-year trajectory of language outcomes for a child with galactosemia
Journal name Journal of Developmental and Behavioral Pediatrics   Check publisher's open access policy
ISSN 0196-206X
Publication date 2013-07
Sub-type Article (original research)
DOI 10.1097/DBP.0b013e31829a7be1
Volume 34
Issue 6
Start page 414
End page 418
Total pages 5
Place of publication Philadelphia, United States
Publisher Lippincott Williams & Wilkins
Collection year 2014
Language eng
Abstract Cross-sectional methodologies have revealed age-related deterioration in cognitive performance, reflecting progressive neurodegenerative change in a minority of children and adolescents with classic galactosemia (GAL). The application of longitudinal methodologies sensitive to age-related changes at the individual level is needed to determine the extent of any possible decline in function in children with GAL. The authors report on the developmental language outcomes of a 9-year-old female with GAL through an examination of her language development over a 7-year period using a performance tracking system based on the use of raw performance scores required for attainment at the 50th percentile for age. Raw scores typically increase systematically over time and are thus more sensitive to developmental changes. Results suggest that there was no decline in the child’s language skills over the course of the investigation. For the case presented, the use of raw scores offered a means of examining the child’s patterns of individual change, which revealed stable language skills over the period of monitoring, perhaps indicating a stable disease process for this particular child. The authors propose this descriptive application of raw performance scores that offers a means to determine neurodevelopmental outcomes in the disorder.
Keyword Galactosemia
Longitudinal methodology
Language development and disorders
Language trajectory
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

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Created: Fri, 26 Apr 2013, 11:25:12 EST by Dr Fiona Lewis on behalf of School of Health & Rehabilitation Sciences