NSort/DB: an intra-nuclear compartment protein database

Willadsen, Kai, Mohamad, Nurul and Boden, Mikael (2012) NSort/DB: an intra-nuclear compartment protein database. Genomics, Proteomics & Bioinformatics, 10 4: 226-229. doi:10.1016/j.gpb.2012.07.001

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Author Willadsen, Kai
Mohamad, Nurul
Boden, Mikael
Title NSort/DB: an intra-nuclear compartment protein database
Journal name Genomics, Proteomics & Bioinformatics   Check publisher's open access policy
ISSN 1672-0229
2210-3244
Publication date 2012-08
Sub-type Article (original research)
DOI 10.1016/j.gpb.2012.07.001
Open Access Status File (Author Post-print)
Volume 10
Issue 4
Start page 226
End page 229
Total pages 4
Place of publication London, United Kingdom
Publisher Elsevier
Collection year 2013
Language eng
Abstract Distinct substructures within the nucleus are associated with a wide variety of important nuclear processes. Structures such as chromatin and nuclear pores have specific roles, while others such as Cajal bodies are more functionally varied. Understanding the roles of these membraneless intra-nuclear compartments requires extensive data sets covering nuclear and compartment-associated proteins. NSort/DB is a database providing access to intra- or sub-nuclear compartment associations for the mouse nuclear proteome. Based on resources ranging from large-scale curated data sets to detailed experiments, this data set provides a high-quality set of annotations of non-exclusive association of nuclear proteins with structures such as promyelocytic leukaemia bodies and chromatin. The database is searchable by protein identifier or compartment, and has a documented web service API. The search interface, web service and data download are all freely available online at http://www.nsort.org/db/. Availability of this data set will enable systematic analyses of the protein complements of nuclear compartments, improving our understanding of the diverse functional repertoire of these structures.
Keyword Nuclear compartments
Nuclear proteins
Web service
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

 
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Created: Wed, 17 Apr 2013, 16:18:48 EST by Mikael Boden on behalf of School of Chemistry & Molecular Biosciences