Treatment and control of scabies

Mounsey, Kate E. and McCarthy, James S. (2013) Treatment and control of scabies. Current Opinion in Infectious Diseases, 26 2: 133-139. doi:10.1097/QCO.0b013e32835e1d57


Author Mounsey, Kate E.
McCarthy, James S.
Title Treatment and control of scabies
Journal name Current Opinion in Infectious Diseases   Check publisher's open access policy
ISSN 0951-7375
1473-6527
Publication date 2013-04
Year available 2013
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1097/QCO.0b013e32835e1d57
Volume 26
Issue 2
Start page 133
End page 139
Total pages 7
Place of publication Philadelphia, PA, United States
Publisher Lippincott Williams & Wilkins
Collection year 2014
Language eng
Formatted abstract
Purpose of Review: The treatment of individual patients with scabies and its control in institutional and community settings remains challenging, with relatively few treatment choices available. In this review, evidence of the efficacy of available treatments will be discussed, and possible emerging drug resistance and new therapeutic directions outlined.

Recent Findings: Although there has been attention on the use of ivermectin for the treatment of ordinary scabies and for mass drug administration, evidence supporting its superiority for both indications over alternative treatment is inconclusive. This is particularly true in light of several case reports of drug resistance in human and veterinary settings when the drug has been intensively used. When used correctly, topical agents such as permethrin and benzyl benzoate are effective. Little research on the development of new and more effective acaricides suitable for human use is underway. While the in-vitro acaricidal properties of several natural products have been documented, these are yet to be evaluated in animal studies or clinical trials.

Summary: When properly administered, chemotherapy for scabies remains effective in most situations. However, with reports of drug resistance increasing and with the need for therapies suitable for use in interventions to control community outbreaks, there is a need to develop new therapies.
Keyword Drug resistance
Ivermectin
Permethrin
Scabies
Treatment
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: Official 2014 Collection
School of Medicine Publications
 
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