A five-year prospective study of quality of life after colorectal cancer

Chambers, Suzanne K., Meng, Xingqiong, Youl, Pip, Aitken, Joanne, Dunn, Jeff and Baade, Peter (2012) A five-year prospective study of quality of life after colorectal cancer. Quality of Life Research, 21 9: 1551-1564. doi:10.1007/s11136-011-0067-5

Author Chambers, Suzanne K.
Meng, Xingqiong
Youl, Pip
Aitken, Joanne
Dunn, Jeff
Baade, Peter
Title A five-year prospective study of quality of life after colorectal cancer
Journal name Quality of Life Research   Check publisher's open access policy
ISSN 0962-9343
Publication date 2012-11
Sub-type Article (original research)
DOI 10.1007/s11136-011-0067-5
Volume 21
Issue 9
Start page 1551
End page 1564
Total pages 14
Place of publication Dordrecht, The Netherlands
Publisher Springer
Collection year 2013
Language eng
Formatted abstract
Purpose Long-term (≥5 years) quality of life after colorectal cancer is not well described. The present study assessed quality of life (QOL) and psychological distress in colorectal cancer survivors more than 5 years to describe changes over time and antecedents of long-term outcomes.
Method A prospective survey of a population-based sample of 763 colorectal cancer patients assessed sociodemographic variables, health behaviors, optimism, threat appraisal, and perceived social support at 5 months postdiagnosis as predictors of QOL and psychological distress 5 years post-diagnosis.
Results QOL improved over time (P < 0.01 for each measure); however, measures of psychological distress remained stable (P > 0.07 for each measure). Risk factors for poorer QOL and/or greater psychological distress included: later stage disease, having a permanent stoma, rectal cancer, fatigue, smoking, being single, low social support, low optimism, and a more negative cancer threat appraisal. Being women, having a pet, having a private health insurance, and receiving both surgery and adjuvant treatment were protective.
Conclusion Consistent with response shift theory, the antecedents of QOL after colorectal cancer are multifactorial and include predisposing socio-demographic, medical, and psychological variables. Psychosocial interventions that target both social support and threat appraisal may be effective for this patient group.
Additional steppedup support may be needed for people from a poorer social environment who have multiple risk factors for poorer adjustment. Health system effects require further investigation.
Keyword Colorectal cancer
Quality of life
Psychological distress
Response shift
Response Shift Theory
Psychological Distress
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: UQ Centre for Clinical Research Publications
Official 2013 Collection
School of Social Science Publications
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Citation counts: TR Web of Science Citation Count  Cited 26 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 29 times in Scopus Article | Citations
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