Open-chain steroidal glycosides, a diverse class of plant saponins

Challinor, Victoria L. and De Voss, James J. (2013) Open-chain steroidal glycosides, a diverse class of plant saponins. Natural Product Reports, 30 3: 429-454. doi:10.1039/c3np20105h


Author Challinor, Victoria L.
De Voss, James J.
Title Open-chain steroidal glycosides, a diverse class of plant saponins
Journal name Natural Product Reports   Check publisher's open access policy
ISSN 0265-0568
1460-4752
Publication date 2013-01
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1039/c3np20105h
Open Access Status Not Open Access
Volume 30
Issue 3
Start page 429
End page 454
Total pages 26
Place of publication Cambridge, United Kingdom
Publisher Royal Society of Chemistry
Collection year 2014
Language eng
Abstract Covering: up to September 2012. Saponins are an important class of plant natural products that consist of a triterpenoid or steroidal skeleton that is glycosylated by varying numbers of sugar units attached at different positions. Steroidal saponins are usually divided into two broad structural classes, namely spirostanol and furostanol saponins. A third, previously unrecognized structural class of plant saponins, the open-chain steroidal saponins, is introduced in this review; these possess an acyclic sidechain in place of the heterocyclic ring/s present in spirostanols and furostanols. Open-chain steroidal saponins are numerous and structurally diverse, with over 150 unique representatives reported from terrestrial plants. Despite this, they have to date been largely overlooked in reviews of plant natural products. This review catalogs the structural diversity of open-chain steroidal saponins isolated from terrestrial plants and discusses aspects of their structure elucidation, biological activities, biosynthesis, and distribution in the plant kingdom. It is intended that this review will provide a point of reference for those working with open-chain steroidal saponins and result in their recognition and inclusion in future reviews of plant saponins.
Keyword Saponins
Steroidal
Open-chain
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collections: Official 2014 Collection
School of Chemistry and Molecular Biosciences
 
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Created: Fri, 15 Mar 2013, 09:56:54 EST by Mrs Louise Nimwegen on behalf of Examinations