A novel composite porous coating approach for bioactive titanium-based orthopedic implants

Qiu, Dong, Zhang, Mingxing and Grondahl, Lisbeth (2013) A novel composite porous coating approach for bioactive titanium-based orthopedic implants. Journal of Biomedical Materials Research Part A, 101 A 3: 862-872. doi:10.1002/jbm.a.34372


Author Qiu, Dong
Zhang, Mingxing
Grondahl, Lisbeth
Title A novel composite porous coating approach for bioactive titanium-based orthopedic implants
Journal name Journal of Biomedical Materials Research Part A   Check publisher's open access policy
ISSN 1549-3296
1552-4965
Publication date 2013-03
Year available 2012
Sub-type Article (original research)
DOI 10.1002/jbm.a.34372
Volume 101 A
Issue 3
Start page 862
End page 872
Total pages 11
Place of publication Hoboken, NJ, United States
Publisher John Wiley & Sons
Collection year 2013
Language eng
Abstract Surface modification of titanium-based implants is considered a highly effective solution to enhance osseointegration. This study describes a novel Ti/hydroxyapatite (HA) composite porous coating produced using a cold spraying technique. Experimental results indicate desirable open-cell structure with 50-150 μm pore size and 60-65% macroporosity. In particular, the reinforced HA particles are exposed to the surface of the coating resulting in enhanced mineralization ability in simulated body fluid. None of the coatings displayed a cytotoxic response in SaOS-2 cells cultured in vitro for up to 48 h. The bond strength between the porous coating and the Ti substrate was found to be 20 MPa. These properties are comparative to or better than products currently on the market and thus this novel coating has potential use in orthopedics.
Keyword Porous coating
Hydroxyapatite
Cold spraying
Bioactivity
Titanium implants
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Article first published online: 12 September 2012.

Document type: Journal Article
Sub-type: Article (original research)
Collections: School of Mechanical & Mining Engineering Publications
Official 2013 Collection
School of Chemistry and Molecular Biosciences
 
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Created: Fri, 01 Mar 2013, 10:30:35 EST by Mrs Louise Nimwegen on behalf of School of Mechanical and Mining Engineering