Microsatellite typing and population structuring of Trypanosoma evansi in Mindanao, Philippines

McInnes, L. M., Dargantes, A. P., Ryan, U. M. and Reid, S. A. (2012) Microsatellite typing and population structuring of Trypanosoma evansi in Mindanao, Philippines. Veterinary Parasitology, 187 1-2: 129-139. doi:10.1016/j.vetpar.2011.12.010


Author McInnes, L. M.
Dargantes, A. P.
Ryan, U. M.
Reid, S. A.
Title Microsatellite typing and population structuring of Trypanosoma evansi in Mindanao, Philippines
Journal name Veterinary Parasitology   Check publisher's open access policy
ISSN 0304-4017
1873-2550
Publication date 2012-06
Sub-type Article (original research)
DOI 10.1016/j.vetpar.2011.12.010
Volume 187
Issue 1-2
Start page 129
End page 139
Total pages 11
Place of publication Amsterdam, The Netherlands
Publisher Elsevier
Collection year 2012
Language eng
Formatted abstract
Trypanosoma evansi, a blood-borne protozoan parasite with an extensive geographical range is the causative agent of the livestock disease known as surra. A total of 140 out of 179 T. evansi isolates collected between 2006 and 2007 from 44 villages (comprising of 16 reported surra outbreaks) in 3 provinces (Agusan del Sur (ADS), Surigao del Sur (SDS) and Agusan del Norte (ADN)) in Mindanao, Philippines were each successfully genotyped using a suite of 7 polymorphic microsatellites. The study identified 16 multi locus genotypes (MLG) within the T. evansi isolates and evidence of the spread of surra outbreaks from one village to another, most likely due to the movement of infected animals. Genotyping provided evidence of population sub-structuring with 3 populations (I, II and III (only 1 isolate)) identified. The most abundant population was II, which was the predominant population in ADS and SDS (p = 0.022). In addition, buffalo mortality was statistically higher in outbreak areas associated with isolates from population I (13.6%) than with isolates from population
II (6.9%) (p = 0.047). The present study has highlighted the utility of microsatellite loci to improve understanding of the epidemiology of T. evansi and in tracking surra outbreaks.
Keyword Trypanosoma evansi
Surra
Epidemic
Microsatellites
Dna
Mindanao
Philippines
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Non HERDC
School of Public Health Publications
 
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Citation counts: TR Web of Science Citation Count  Cited 7 times in Thomson Reuters Web of Science Article | Citations
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Created: Wed, 16 Jan 2013, 15:17:09 EST by Geraldine Fitzgerald on behalf of School of Public Health