Assessing the global burden of ischemic heart disease Part 1: methods for a systematic review of the global epidemiology of ischemic heart disease in 1990 and 2010

Moran, Andrew E., Oliver, John T., Mirzaie, Masoud, Forouzanfar, Mohammad H., Chilov, Marina, Anderson, Laurie, Morrison, Janina L., Khan, Aayla, Zhang, Nasen, Haynes, Norrisa, Tran, Jackie, Murphy, Adrianna, Degennaro, Vincent, Roth, Gregory, Zhao, Dong, Peer, Nasheeta, Pichon-Riviere, Andres, Rubinstein, Adolfo, Pogosova, Nana, Prabhakaran, Dorairaj, Naghavi, Mohsen, Ezzati, Majid and Mensah, George A. (2012) Assessing the global burden of ischemic heart disease Part 1: methods for a systematic review of the global epidemiology of ischemic heart disease in 1990 and 2010. Global Heart, 7 4: 315-329. doi:10.1016/j.gheart.2012.10.004

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Author Moran, Andrew E.
Oliver, John T.
Mirzaie, Masoud
Forouzanfar, Mohammad H.
Chilov, Marina
Anderson, Laurie
Morrison, Janina L.
Khan, Aayla
Zhang, Nasen
Haynes, Norrisa
Tran, Jackie
Murphy, Adrianna
Degennaro, Vincent
Roth, Gregory
Zhao, Dong
Peer, Nasheeta
Pichon-Riviere, Andres
Rubinstein, Adolfo
Pogosova, Nana
Prabhakaran, Dorairaj
Naghavi, Mohsen
Ezzati, Majid
Mensah, George A.
Title Assessing the global burden of ischemic heart disease Part 1: methods for a systematic review of the global epidemiology of ischemic heart disease in 1990 and 2010
Journal name Global Heart   Check publisher's open access policy
ISSN 2211-8160
2211-8179
Publication date 2012-12
Sub-type Article (original research)
DOI 10.1016/j.gheart.2012.10.004
Volume 7
Issue 4
Start page 315
End page 329
Total pages 15
Place of publication Amsterdam, Netherlands
Publisher Elsevier
Collection year 2013
Language eng
Formatted abstract
Methods: The disease model of IHD for the GBD 2010 Study included IHD death and 3 sequelae: myocardial infarction, heart failure, and angina pectoris. Medline, EMBASE, and LILACS were searched for IHD epidemiology studies in GBD high-income and low- and middle-income regions published between 1980 and 2008 using a systematic protocol validated by regional IHD experts. Data from included studies were supplemented with unpublished data from selected high-quality surveillance and survey studies. The epidemiologic parameters of interest were incidence, prevalence, case fatality, and mortality.

Results:
Literature searches yielded 40,205 unique papers, of which 1,801 met initial screening criteria. Upon detailed review of full text papers, 137 published studies were included. Unpublished data were obtained from 24 additional studies. Data were sufficient for high-income regions, but missing or sparse in many low- and middle-income regions, particularly Sub-Saharan Africa.

Conclusions: A systematic review for the GBD 2010 Study provided IHD epidemiology estimates for most world regions, but highlighted the lack of information about IHD in Sub-Saharan Africa and other low-income regions. More complete knowledge of the global burden of IHD will require improved IHD surveillance programs in all world regions.

Ischemic heart disease (IHD) is caused by insufficient oxygen delivery to meet the metabolic demands of heart muscle. IHD can be caused by a failure to adequately perfuse cardiac myocytes with oxygenated blood (failure of supply) and/or to increase myocyte oxygen demand [1]. Failure of oxygen supply most commonly occurs due to a fixed narrowing or acute rupture or dissection of an atherosclerotic coronary artery, or less commonly due to coronary artery spasm, embolism, or vasculitis. Inadequate oxygen supply may also occur due to severe anemia or systemic hypotension. Ischemia due to increased oxygen demand may be caused by sustained tachycardia, uncontrolled hypertension, or heart failure. Less commonly, IHD may occur due to cardiac revascularization procedures [1]. IHD can lead to acute myocardial necrosis (acute myocardial infarction [AMI]), fatal arrhythmia, or to a number of chronic sequelae, most prominently stable angina pectoris or heart failure (Fig. 1).
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2013 Collection
School of Public Health Publications
 
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Created: Wed, 16 Jan 2013, 13:34:04 EST by Geraldine Fitzgerald on behalf of School of Public Health