Anticancer activity of Carica papaya: a review

Nguyen, Thao T. T., Shaw, Paul N., Parat, Marie-Odile and Hewavitharana, Amitha K. (2013) Anticancer activity of Carica papaya: a review. Molecular Nutrition and Food Research, 57 1: 153-164. doi:10.1002/mnfr.201200388

Author Nguyen, Thao T. T.
Shaw, Paul N.
Parat, Marie-Odile
Hewavitharana, Amitha K.
Title Anticancer activity of Carica papaya: a review
Formatted title
Anticancer activity of Carica papaya: a review
Journal name Molecular Nutrition and Food Research   Check publisher's open access policy
ISSN 1613-4125
Publication date 2013-01
Year available 2012
Sub-type Article (original research)
DOI 10.1002/mnfr.201200388
Volume 57
Issue 1
Start page 153
End page 164
Total pages 12
Place of publication Weinheim, Germany
Publisher Wiley
Collection year 2013
Language eng
Formatted abstract
Carica papaya is widely cultivated in tropical and subtropical countries and is used as food as well as traditional medicine to treat a range of diseases. Increasing anecdotal reports of its effects in cancer treatment and prevention, with many successful cases, have warranted that these pharmacological properties be scientifically validated. A bibliographic search was conducted using the key words “papaya”, “anticancer”, and “antitumor” along with cross-referencing. No clinical or animal cancer studies were identified and only seven in vitro cell-culture-based studies were reported; these indicate that C. papaya extracts may alter the growth of several types of cancer cell lines. However, many studies focused on specific compounds in papaya and reported bioactivity including anticancer effects. This review summarizes the results of extract-based or specific compound-based investigations and emphasizes the aspects that warrant future research to explore the bioactives in C. papaya for their anticancer activities.
Keyword Anticancer
Carica papaya
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Article first published online: 5 DEC 2012

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2013 Collection
School of Pharmacy Publications
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 15 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 21 times in Scopus Article | Citations
Google Scholar Search Google Scholar
Created: Mon, 14 Jan 2013, 10:29:02 EST by Myrtle Sahabandu on behalf of School of Pharmacy