Adherence to MRI protocol consensus guidelines in multiple sclerosis: an Australian multi-centre study

Curley, Michael, Josey, Lawrence, Lucas, Robyn, Dear, Keith, Taylor, Bruce V., Coulthard, Alan and the Ausimmune Investigator Group (2012) Adherence to MRI protocol consensus guidelines in multiple sclerosis: an Australian multi-centre study. Journal of Medical Imaging and Radiation Oncology, 56 6: 594-598. doi:10.1111/1754-9485.12000

Author Curley, Michael
Josey, Lawrence
Lucas, Robyn
Dear, Keith
Taylor, Bruce V.
Coulthard, Alan
the Ausimmune Investigator Group
Total Author Count Override 19
Title Adherence to MRI protocol consensus guidelines in multiple sclerosis: an Australian multi-centre study
Journal name Journal of Medical Imaging and Radiation Oncology   Check publisher's open access policy
ISSN 1754-9477
Publication date 2012-12
Sub-type Article (original research)
DOI 10.1111/1754-9485.12000
Volume 56
Issue 6
Start page 594
End page 598
Total pages 5
Place of publication Richmond, VIC, Australia
Publisher Wiley-Blackwell Publishing Asia
Collection year 2013
Language eng
Formatted abstract
Introduction Multiple sclerosis (MS) is a debilitating disease that causes significant morbidity within a young demographic. Diagnostic guidelines for MS have evolved, and imaging has played an increasingly important role in diagnosis over the last two decades. For imaging to contribute to diagnosis in a meaningful way, it must be reproducible. Consensus guidelines for MRI in MS exist to define correct sequence type and imaging technique, but it is not clear to what extent they are followed. This study reviewed MRI studies performed on Australian individuals presenting with a first clinical diagnosis of central nervous system demyelination (FCD) for adherence to published guidelines and discussed practical implementation of MS guidelines in light of recent updates. Methods The Ausimmune study was a prospective case control study of Australian participants presenting with FCD from 2003 to 2006. Baseline cranial and spinal cord MRI studies of 226 case participants from four separate Australian regions were reviewed. MRI sequences were classified according to anatomical location, slice plane, tissue weighting and use of gadolinium-containing contrast media. Results were compared with the 2003 Consortium of Multiple Sclerosis Centres MRI protocol for the diagnosis of MS. Results The composition of core cranial MRI sequences performed varied across the 226 scans. Of the studies, 91% included sagittal fluid attenuated inversion recovery (FLAIR) sequences. Cranial axial T2-weighted, axial FLAIR and axial proton density-weighted sequences were performed in 88%, 60% and 16% (respectively) of scans. Only 25% of the studies included a T1-weighted contrast-enhanced sequence. Concordance with the guidelines in all sequences was very low (2). Conclusion Only a small number of MRI investigations performed included all of the sequences stipulated by consensus guidelines. This is likely due to poor awareness in the imaging community of the guidelines and the rationale behind certain sequences. Radiologists with a sub-speciality interest in neuroradiology should take ownership of this issue and ensure that recommended imaging guidelines are followed.
Keyword Brain
Demyelinating diseases
Multiple sclerosis
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2013 Collection
School of Medicine Publications
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Citation counts: TR Web of Science Citation Count  Cited 3 times in Thomson Reuters Web of Science Article | Citations
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