Root discolouration following short-term application of steroid medicaments containing clindamycin, doxycycline or demeclocycline

Chen, Belinda K., George, Roy and Walsh, Laurence J. (2012) Root discolouration following short-term application of steroid medicaments containing clindamycin, doxycycline or demeclocycline. Australian Endodontic Journal, 38 3: 124-128. doi:10.1111/aej.12000


Author Chen, Belinda K.
George, Roy
Walsh, Laurence J.
Title Root discolouration following short-term application of steroid medicaments containing clindamycin, doxycycline or demeclocycline
Journal name Australian Endodontic Journal   Check publisher's open access policy
ISSN 1329-1947
1747-4477
Publication date 2012-12
Sub-type Article (original research)
DOI 10.1111/aej.12000
Volume 38
Issue 3
Start page 124
End page 128
Total pages 5
Place of publication Richmond, Vic., Australia
Publisher Wiley-Blackwell Publishing
Collection year 2013
Language eng
Formatted abstract
Discolouration of teeth following application of intra-canal antibiotic pastes is a clinical concern. This laboratory study compared the extent of tooth discolouration from three antibiotic pastes over 4 weeks. A total of 120 root samples were prepared and the canals filled with either Ledermix (demeclocyline), Odontopaste (clindamycin) or DoxyPaste (doxycycline). Roots were photographed before and 2 or 4 weeks after incubation at 37°C and 100% humidity in complete darkness in opaque containers. Digital images were standardised and assessed for changes in luminosity. Ledermix paste caused the most discolouration of the three, at both 2 and 4 weeks. There was no significant difference between DoxyPaste and Odontopaste at 2 weeks, whereas at 4 weeks, DoxyPaste caused a greater decrease in luminosity (P < 0.05), darkening more over the second 2-week interval than treatment with Odontopaste (P < 0.05). Under zero light conditions, staining with Ledermix can still occur; indicating non-light-based chemical reactions in the staining process. Doxycycline containing intra-canal medicaments caused less staining despite being a tetracycline-based medicament.
Keyword Clindamycin
Doxycycline
Endodontics
Root staining
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2013 Collection
School of Dentistry Publications
 
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Citation counts: TR Web of Science Citation Count  Cited 5 times in Thomson Reuters Web of Science Article | Citations
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Created: Fri, 04 Jan 2013, 14:36:09 EST by Professor Laurence Walsh on behalf of School of Dentistry