Tractography-based parcellation of the human left inferior parietal lobule

Wang, Jiaojian, Fan, Lingzhong, Zhang, Yu, Liu, Yong, Jiang, Di, Zhang, Yuanchao, Yu, Chunshui and Jiang, Tianzi (2012) Tractography-based parcellation of the human left inferior parietal lobule. Neuroimage, 63 2: 641-652. doi:10.1016/j.neuroimage.2012.07.045


Author Wang, Jiaojian
Fan, Lingzhong
Zhang, Yu
Liu, Yong
Jiang, Di
Zhang, Yuanchao
Yu, Chunshui
Jiang, Tianzi
Title Tractography-based parcellation of the human left inferior parietal lobule
Journal name Neuroimage   Check publisher's open access policy
ISSN 1053-8119
1095-9572
Publication date 2012-11
Sub-type Article (original research)
DOI 10.1016/j.neuroimage.2012.07.045
Volume 63
Issue 2
Start page 641
End page 652
Total pages 12
Place of publication Amsterdam, Netherlands
Publisher Elsevier
Collection year 2013
Language eng
Abstract The inferior parietal lobule (IPL) is a functionally and anatomically heterogeneous region. Much of the information about the anatomical connectivity and parcellation of this region was obtained from histological studies on non-human primates. However, whether these findings from non-human primates can be applied to the human inferior parietal lobule, especially the left inferior parietal lobule, which shows evidence of considerable evolution from primates to humans, remains unclear. In this study, diffusion MRI was employed to investigate the anatomical connectivities of the human left inferior parietal lobule. Using a new algorithm, spectral clustering with edge-weighted centroidal voronoi tessellations, to search for regional variations in the probabilistic connectivity profiles of all left inferior parietal lobule voxels with all the rest of the brain identified six subregions with distinctive connectivity properties in the left inferior parietal lobule. Consistent with cytoarchitectonic findings, four subregions were found in the left supramarginal gyrus and two subregions in the left angular gyrus. The specific connectivity patterns of each subregion of the left inferior parietal lobule were supported by both the anatomical and functional connectivity properties for each subregion, as calculated by a meta-analysis-based target method and by voxel-based whole brain anatomical and functional connectivity analyses. The proposed parcellation scheme for the human left inferior parietal lobule and the maximum probability map for each subregion may facilitate more detailed future studies of this brain area.
Keyword Diffusion tensor imaging
Left inferior parietal lobule
Meta-analysis
Parcellation
Resting-state
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Available online: 27 July 2012.

Document type: Journal Article
Sub-type: Article (original research)
Collections: Queensland Brain Institute Publications
Official 2013 Collection
Centre for Advanced Imaging Publications
 
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