Joint allelic effects on fitness and metric traits

McGuigan, Katrina and Blows, Mark W. (2013) Joint allelic effects on fitness and metric traits. Evolution, 67 4: 1131-1142. doi:10.1111/j.1558-5646.2012.01833.x


Author McGuigan, Katrina
Blows, Mark W.
Title Joint allelic effects on fitness and metric traits
Journal name Evolution   Check publisher's open access policy
ISSN 0014-3820
1558-5646
Publication date 2013-04
Year available 2012
Sub-type Article (original research)
DOI 10.1111/j.1558-5646.2012.01833.x
Volume 67
Issue 4
Start page 1131
End page 1142
Total pages 12
Place of publication Oxford, United Kingdom
Publisher Wiley-Blackwell
Collection year 2013
Language eng
Abstract Theoretical explanations of empirically observed standing genetic variation, mutation, and selection suggest that many alleles must jointly affect fitness and metric traits. However, there are few direct demonstrations of the nature and extent of these pleiotropic associations. We implemented a mutation accumulation (MA) divergence experimental design in Drosophila serrata to segregate genetic variants for fitness and metric traits. By exploiting naturally occurring MA line extinctions as a measure of line-level total fitness, manipulating sexual selection, and measuring productivity we were able to demonstrate genetic covariance between fitness and standard metric traits, wing size and shape. Larger size was associated with lower total fitness and male sexual fitness, but higher productivity. Multivariate wing shape traits, capturing major axes of wing shape variation among MA lines, evolved only in the absence of sexual selection, and to the greatest extent in lines that went extinct, indicating that mutations contributing wing shape variation also typically had deleterious effects on both total fitness and male sexual fitness. This pleiotropic covariance of metric traits with fitness will drive their evolution, and generate the appearance of selection on the metric traits even in the absence of a direct contribution to fitness.
Keyword Sexual selection
Viability
Productivity
Wing
Size
Drosophila serrata
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Published online 29 November 2012

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2013 Collection
School of Biological Sciences Publications
 
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Created: Tue, 13 Nov 2012, 10:39:39 EST by Gail Walter on behalf of School of Biological Sciences