Spontaneous ocular squamous cell carcinoma in twin goats: pathological and biomolecular studies

Mara, M., Di Guardo, G., Venuti, A., Marruchella, G., Palmieri, C., De Rugeriis, M., Petrizzi, L., Simeone, P., Rizzo, C. and Della Salda, L. (2005) Spontaneous ocular squamous cell carcinoma in twin goats: pathological and biomolecular studies. Journal of Comparative Pathology, 132 1: 96-100. doi:10.1016/j.jcpa.2004.06.007


Author Mara, M.
Di Guardo, G.
Venuti, A.
Marruchella, G.
Palmieri, C.
De Rugeriis, M.
Petrizzi, L.
Simeone, P.
Rizzo, C.
Della Salda, L.
Title Spontaneous ocular squamous cell carcinoma in twin goats: pathological and biomolecular studies
Journal name Journal of Comparative Pathology   Check publisher's open access policy
ISSN 0021-9975
1532-3129
Publication date 2005
Sub-type Article (original research)
DOI 10.1016/j.jcpa.2004.06.007
Volume 132
Issue 1
Start page 96
End page 100
Total pages 5
Place of publication London, United Kingdom
Publisher Elsevier
Collection year 2005
Language eng
Formatted abstract
Ocular squamous cell carcinoma (OSCC) is a well-characterized tumour occurring spontaneously in cattle and other mammalian species but not previously reported in the goat. This report describes the histological features of well-differentiated OSCCs in twin goats. Biomolecular investigations led to the identification of Papillomavirus-related DNA sequences within the neoplastic ocular parenchyma of both animals, but immunohistochemical and ultrastructural studies failed to demonstrate viral particles. A putative role of Papillomavirus in the aetiology of OSCC is discussed, together with other possible causative factors.
Keyword Eye
Goat
Koilocyte
Ocular squamous cell carcinoma
Papillomavirus
Viral Infection
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Veterinary Science Publications
 
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Created: Sun, 21 Oct 2012, 17:11:16 EST by Chiara Palmieri on behalf of School of Veterinary Science