The effect of surfactant on the dissolution of porcine pulpal tissue by Sodium Hypochlorite solutions

Clarkson, Roger M., Kidd, Bruce, Evans, Gareth E. and Moule, Alex J. (2012) The effect of surfactant on the dissolution of porcine pulpal tissue by Sodium Hypochlorite solutions. Journal of Endodontics, 38 9: 1257-1260. doi:10.1016/j.joen.2012.05.013

Author Clarkson, Roger M.
Kidd, Bruce
Evans, Gareth E.
Moule, Alex J.
Total Author Count Override 4
Title The effect of surfactant on the dissolution of porcine pulpal tissue by Sodium Hypochlorite solutions
Journal name Journal of Endodontics   Check publisher's open access policy
ISSN 0099-2399
Publication date 2012-09
Sub-type Article (original research)
DOI 10.1016/j.joen.2012.05.013
Open Access Status
Volume 38
Issue 9
Start page 1257
End page 1260
Total pages 4
Place of publication Philadelphia, United States
Publisher Elsevier
Collection year 2013
Language eng
Formatted abstract
Introduction: A previous study of the relative dental pulp-dissolving abilities of Milton brand of sodium hypochlorite (NaOCl) and other surfactant-containing NaOCl solutions produced specifically for endodontic treatment showed a markedly better performance of the surfactant-containing product that was not explained by differences in active chlorine content. This study investigated whether the presence of surfactant in the NaOCl solutions was responsible for the difference in dissolution times seen in the previous study.

Methods: Circular samples 2.5 mm in diameter were punched out of the pulps of mandibular incisor teeth from young pigs. The 4 NaOCl solutions tested were Hypochlor 1% and Hypochlor 4% forte, which contained surfactant, and 2 identical solutions without surfactant. Twenty pulp specimens were immersed in 20 individual 25-mL aliquots of each of the 4 NaOCl solutions and observed while stirring until dissolution was complete. The time to dissolution of each sample was determined by stopwatch. Dissolution times for each solution were averaged and compared statistically in R (version 2.12.0) by using multiple regression with nominal active chlorine content as a covariate.

Results: No statistical difference was detected between the dissolution times for either of the Hypochlor solutions with and without surfactant.

Conclusions: The addition of surfactant alone does not appear to improve the abilities of NaOCl to dissolve dental pulp tissue.
Keyword Pulp tissue dissolution
Sodium hypochlorite
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: School of Mathematics and Physics
Official 2013 Collection
School of Dentistry Publications
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