Experimental infections with Campylobacter fetus subspecies venerealis in cattle

Ardila Avila, Andres, Indjein, Lea, Koya, Ameera, Lew-Tabor, Ala, Venus, Bronywn, de Weit, Sharon C., Power, John, Greer, Ristan M., Boe-Hansen, Gry and McGowan, Michael (2012). Experimental infections with Campylobacter fetus subspecies venerealis in cattle. In: IVVDC 2012: 6th International Veterinary Vaccines and Diagnostics Conference, Cairns, Australia, (). 29 July - 1 August 2012.

Author Ardila Avila, Andres
Indjein, Lea
Koya, Ameera
Lew-Tabor, Ala
Venus, Bronywn
de Weit, Sharon C.
Power, John
Greer, Ristan M.
Boe-Hansen, Gry
McGowan, Michael
Title of paper Experimental infections with Campylobacter fetus subspecies venerealis in cattle
Formatted title
Experimental infections with Campylobacter fetus subspecies venerealis in cattle
Conference name IVVDC 2012: 6th International Veterinary Vaccines and Diagnostics Conference
Conference location Cairns, Australia
Conference dates 29 July - 1 August 2012
Publication Year 2012
Sub-type Poster
Language eng
Formatted Abstract/Summary
Development of effective protocols to replicate the transmission of C. fetus subsp. venerealis in cattle is critical for the evaluation of the biology of the organism as well as the host immune response. Â Protocols for experimental infections with C. fetus venerealis in bulls and heifers were developed. A total of 6 Brahman bulls and 11 Brahman heifers were randomly allocated to four experimental groups containing exposed and unexposed animals. One group of bulls and one group of heifers were challenged by experimental exposure by intrapreputial and intracervical inoculation with a C. fetus venerealis suspension respectively. The remaining groups were challenged by natural mating with previously infected animals. Detection of C. fetus venerealis using culture and real-time PCR in smegma samples from bulls and cervico-vaginal samples from heifers; and macro and histological examination of tissue samples from the reproductive tracts collected after slaughter were performed. C. fetus venerealis was detected by culture and/or real time PCR in all groups post-challenge. Experimental exposure was more effective in establishing infection in bulls and heifers and the infectious status appeared to last longer (up to 10 weeks in bulls and 7 weeks in heifers). There was minimal cellular inflammatory response after experimental and natural challenge.
Q-Index Code EX
Q-Index Status Provisional Code
Institutional Status UQ

 
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Created: Fri, 19 Oct 2012, 14:14:12 EST by Dr Gry Boe-hansen on behalf of School of Veterinary Science