Acute effects of treadmill running on lipoprotein(a) levels in males and females

Hubinger, Lyle, Mackinnon, Laurel Traeger, Barber, Lee, Mccosker, Jane, Howard, Alf and Lepre, Frank (1997) Acute effects of treadmill running on lipoprotein(a) levels in males and females. Medicine and Science in Sports and Exercise, 29 4: 436-442. doi:10.1097/00005768-199704000-00003


Author Hubinger, Lyle
Mackinnon, Laurel Traeger
Barber, Lee
Mccosker, Jane
Howard, Alf
Lepre, Frank
Title Acute effects of treadmill running on lipoprotein(a) levels in males and females
Journal name Medicine and Science in Sports and Exercise   Check publisher's open access policy
ISSN 0195-9131
1530-0315
Publication date 1997-04
Sub-type Article (original research)
DOI 10.1097/00005768-199704000-00003
Volume 29
Issue 4
Start page 436
End page 442
Total pages 7
Place of publication Philadelphia, PA, United States
Publisher Lippincott Williams & Wilkins
Language eng
Formatted abstract This investigation examined the acute response of serum lipoprotein(a) (Lp(a)) concentration immediately after, and during several days following, level and downhill motorized treadmill running. Eight males ran for 1 h on a level motorized treadmill at an intensity producing 90% maximum heart rate (MHR). On a separate occasion, three males and three females performed downhill (negative 13.4% incline) treadmill running at an intensity producing 75-80% MHR. For both protocols, serial blood samples were taken pre- and post-exercise and at the same time of day 1, 3, 5, and 7 days following exercise. Levels of Lp(a), creatine kinase (CK), C-reactive protein (CRP), and ferritin were measured. Repeated measures statistical analysis (Friedman ANOVA) showed no significant change in the median level of Lp(a) (level run, 5.0 mg · dl-1; downhill run, 7.45 mg · dl-1) across time following either protocol. After level running, ferritin levels 5 and 7 d post-exercise were significantly (P < 0.05) lower compared with immediately and 1 d post- exercise measures (Friedman ANOVA). Following level running, the Wilcoxon signed rank test showed significant (P < 0.05) elevations in CK levels immediately, 1 and 5 d post exercise compared with pre-exercise values. Following downhill running, CK level was significantly elevated up to 3 d post-exercise (Wilcoxon signed rank). Calculated plasma volume did not change significantly following either protocol. These data suggest that Lp(a) does not change acutely in response to level or downhill treadmill running up to 60 min duration.
Keyword Eccentric exercise
Acute response
Acute phase reactants
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collection: School of Medicine Publications
 
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Created: Wed, 17 Oct 2012, 16:13:35 EST by Naomi Westwood on behalf of Paediatrics & Child Health - RBWH