Assemblies of biomaterials in mesoporous media

Vinu, Ajayan, Miyahara, Masahiko and Ariga, Katsuhiko (2006) Assemblies of biomaterials in mesoporous media. Journal of Nanoscience and Nanotechnology, 6 6: 1510-1532. doi:10.1166/jnn.2006.253

Author Vinu, Ajayan
Miyahara, Masahiko
Ariga, Katsuhiko
Title Assemblies of biomaterials in mesoporous media
Journal name Journal of Nanoscience and Nanotechnology   Check publisher's open access policy
ISSN 1533-4880
Publication date 2006-06
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1166/jnn.2006.253
Volume 6
Issue 6
Start page 1510
End page 1532
Total pages 23
Place of publication Valencia, CA United States
Publisher American Scientific Publishers
Collection year 2006
Language eng
Formatted abstract
Assemblies of biomaterials onto mechanically stable inorganic structure are advantageous for the practical applications because of the potential to improve the stability and performance of biomaterials in the biocatalytic processes. Among many kinds of inorganic materials, mesoporous materials such as mesoporous silica and mesoporous carbon have attracted special attention owing to their well-defined structures and perfectly controlled pore geometries, which would lead to unique functions such as size selective adsorption of biomaterials. In the first part of this review, adsorption behaviors of proteins, enzymes, vitamins, and amino acids in aqueous solutions onto mesoporous media are systematically explained. Pore geometries (pore diameter and volume) of mesoporous materials are the crucial factors for the size selective adsorption of biomaterials, especially proteins, which often have a size comparable to pore dimension. The studies on the adsorption of biomaterials on the mesoporous carbon reveal that hydrophobic interaction between guest molecules and surface of the mesoporous materials is an important parameter which controls the amount of biomaterials adsorption. Enhanced adsorption of biomaterials was commonly observed at their isoelectric point, where electrostatic repulsion is minimized between the biomaterials. In addition, several functions such as biomolecular separation, reactor function, controlled drug release, and photochemical properties are discussed in the latter sections. Studies on assemblies of biomaterials in mesoporous media are still in initial stage, but the development of appropriately designed mesoporous materials would powerfully promote researches in these fascinating unexplored fields.
Keyword Mesoporous silica
Mesoporous Carbon
Amino acids
Drug release
Q-Index Code C1
Q-Index Status Provisional Code
Institutional Status Non-UQ

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
Collection: Australian Institute for Bioengineering and Nanotechnology Publications
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Citation counts: TR Web of Science Citation Count  Cited 92 times in Thomson Reuters Web of Science Article | Citations
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