Infant formulas for preterm infants: in-hospital and post-discharge

Tudehope, David I., Page, Denise and Gilroy, Melissa (2012) Infant formulas for preterm infants: in-hospital and post-discharge. Journal of Paediatrics and Child Health, 48 9: 768-776. doi:10.1111/j.1440-1754.2012.02533.x


Author Tudehope, David I.
Page, Denise
Gilroy, Melissa
Title Infant formulas for preterm infants: in-hospital and post-discharge
Journal name Journal of Paediatrics and Child Health   Check publisher's open access policy
ISSN 1034-4810
1440-1754
Publication date 2012-09
Sub-type Critical review of research, literature review, critical commentary
DOI 10.1111/j.1440-1754.2012.02533.x
Volume 48
Issue 9
Start page 768
End page 776
Total pages 9
Place of publication Oxford, United Kingdom
Publisher Wiley-Blackwell Publishing
Collection year 2013
Language eng
Abstract The availability and composition of preterm and post-discharge formulas (PDFs) have undergone considerable changes over the last decade. Human milk, supplemented with multi-component fortifier, is the preferred feed for very preterm infants as it has beneficial effects for both short- and long-term outcomes compared with formula. If supply of mother's milk or donor milk is inadequate, a breast milk substitute specifically designed for premature infants is the next option. Preterm formula is intended to provide nutrient intakes to match intrauterine growth and nutrient accretion rates and is enriched with energy, macronutrients, minerals, vitamins, and trace elements compared with term infant formulas. Post-natal longitudinal growth failure has been reported almost universally in extremely preterm infants. Since 2009, a nutritionally enriched PDF specifically designed for preterm infants post hospital discharge with faltering growth has been available in Australia and New Zealand. This formula is an intermediary between preterm and term formulas and contains more energy (73 kcal/100 mL), protein (1.9 g/100 mL), minerals, vitamins, and trace elements than term formulas. Although the use of a PDF is based on sound nutritional knowledge, the 2012 Cochrane Systematic Review of 10 trials comparing feeding preterm infants with PDF and term formula did not demonstrate any short- or long-term benefits. Health professionals need to make individual decisions on whether and how to use PDF.
Keyword Formula
Growth
Infant nutrition
Preterm infant
Q-Index Code CX
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Article first published online: 12 September 2012.

Document type: Journal Article
Sub-type: Critical review of research, literature review, critical commentary
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