A bigger picture: classical cadherins and the dynamic actin cytoskeleton

Ratheesh, Aparna and Yap, Alpha S. (2012) A bigger picture: classical cadherins and the dynamic actin cytoskeleton. Nature Reviews Molecular Cell Biology, 13 10: 673-679.


Author Ratheesh, Aparna
Yap, Alpha S.
Title A bigger picture: classical cadherins and the dynamic actin cytoskeleton
Journal name Nature Reviews Molecular Cell Biology   Check publisher's open access policy
ISSN 1471-0072
1471-0080
Publication date 2012-10
Sub-type Article (original research)
DOI 10.1038/nrm3431
Volume 13
Issue 10
Start page 673
End page 679
Total pages 7
Place of publication London, United Kingdom
Publisher Nature Publishing Group
Collection year 2013
Language eng
Abstract Classical cadherin adhesion receptors influence tissue integrity in health and disease. Their biological function is intimately linked to the actin cytoskeleton. To date, research has largely focused on identifying the molecular mechanisms that physically couple cadherin to cortical actin filaments. However, the junctional cytoskeleton is dynamic. Recent developments in understanding how filament dynamics and organization in the junctional cytoskeleton are controlled provide new insights into how the actin cytoskeleton regulates cadherin junctions in health and disease.
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ
Additional Notes Published under Perspectives: opinion

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2013 Collection
Institute for Molecular Bioscience - Publications
 
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Created: Thu, 11 Oct 2012, 15:04:32 EST by Susan Allen on behalf of Institute for Molecular Bioscience