The role of regulatory RNA in cognitive evolution

Barry, Guy and Mattick, John S. (2012) The role of regulatory RNA in cognitive evolution. Trends In Cognitive Sciences, 16 10: 497-503. doi:10.1016/j.tics.2012.08.007

Author Barry, Guy
Mattick, John S.
Title The role of regulatory RNA in cognitive evolution
Journal name Trends In Cognitive Sciences   Check publisher's open access policy
ISSN 1364-6613
Publication date 2012-10
Sub-type Article (original research)
DOI 10.1016/j.tics.2012.08.007
Volume 16
Issue 10
Start page 497
End page 503
Total pages 7
Place of publication London, United Kingdom
Publisher Elsevier
Collection year 2013
Language eng
Abstract The evolution of the human brain has resulted in the emergence of higher-order cognitive abilities, such as reasoning, planning and social awareness. Although there has been a concomitant increase in brain size and complexity, and component diversification, we argue that RNA regulation of epigenetic processes, RNA editing, and the controlled mobilization of transposable elements have provided the major substrates for cognitive advance. We also suggest that these expanded capacities and flexibilities have led to the collateral emergence of psychiatric fragilities and conditions.
Keyword Higher-order
Cognitive abilities
Epigenetic processes
RNA editing
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

Document type: Journal Article
Sub-type: Article (original research)
Collections: Official 2013 Collection
Institute for Molecular Bioscience - Publications
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Citation counts: TR Web of Science Citation Count  Cited 23 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 28 times in Scopus Article | Citations
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Created: Thu, 11 Oct 2012, 14:52:51 EST by Susan Allen on behalf of Institute for Molecular Bioscience