Fetal microchimerism in skin wound healing

Nassar, Dany, Khosrotehrani, Kiarash and Aractingi, Selim (2012) Fetal microchimerism in skin wound healing. Chimerism, 2 3: 45-47.

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Author Nassar, Dany
Khosrotehrani, Kiarash
Aractingi, Selim
Title Fetal microchimerism in skin wound healing
Journal name Chimerism
Publication date 2012-04-01
Sub-type Article
DOI 10.4161/chim.20739
Volume number 2
Issue number 3
ISSN 1938-1956; 1938-1964
Start page 45
End page 47
Total pages 3
Place of publication Austin, TX, United States
Publisher Landes Bioscience
Collection year 2013
Language eng
Abstract Skin wound healing is a complex regenerative process involving various cell types. We recently investigated whether fetal microchimeric cells (FMCs) acquired during gestation contribute to maternal wound healing and used fetal microchimerism to investigate the recruitment of distant endothelial progenitor cells in skin wounds. Our study showed that fetal progenitor cells are recruited into maternal wounds and participate in inflammation and angiogenesis. These fetal cells might have beneficial effects in situations of maternal defective healing, and might also modify the adult maternal wound environment toward a scarless fetal-like wound healing.
Keyword Fetal stem cells
Microchimerism
Angiogenesis
Inflammation
Wound healing
Skin
Regeneration
Q-Index Code C1
Q-Index Status Confirmed Code
Institutional Status UQ

 
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Created: Thu, 04 Oct 2012, 09:40:19 EST by Roheen Gill on behalf of UQ Centre for Clinical Research